Results 71 to 80 of about 2,131,360 (300)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Sequential Hierarchical Pattern Clustering [PDF]

open access: yes, 2009
Clustering is a widely used unsupervised data analysis technique in machine learning. However, a common requirement amongst many existing clustering methods is that all pairwise distances between patterns must be computed in advance.
Niranjan, Mahesan   +5 more
core   +2 more sources

Clustering graph data: the roadmap to spectral techniques

open access: yesDiscover Artificial Intelligence
Graph data models enable efficient storage, visualization, and analysis of highly interlinked data, by providing the benefits of horizontal scalability and high query performance.
Rahul Mondal   +5 more
doaj   +1 more source

Comparative Analysis of Predictive Algorithms for Performance Measurement

open access: yesIEEE Access
Predictive algorithms, also known as mathematical models, utilize historical data to accurately predict future outcomes. These algorithms identify patterns and relationships within the data, resulting in precise predictions.
Swati Gupta, Bal Kishan, Preeti Gulia
doaj   +1 more source

Fuzzy clustering algorithms and validity indices for distributed data [PDF]

open access: yes, 2014
This chapter presents a unified framework to generalize a number of fuzzy clustering algorithms to handle distributed data in an exact way, i.e., with no approximation of results with respect to their original centralized versions.
R. J. G. B. Campello   +6 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Large scale clustering of protein sequences with FORCE - a layout based heuristic for weighted cluster editing [PDF]

open access: yes, 2007
Wittkop T, Baumbach J, Lobo FP, Rahmann S. Large scale clustering of protein sequences with FORCE - a layout based heuristic for weighted cluster editing. BMC Bioinformatics.
Wittkop, Tobias   +11 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Fermion cluster algorithms [PDF]

open access: yesNuclear Physics B - Proceedings Supplements, 2000
LATTICE99 (algorithms & Machines), 3 pages, 4 eps figures, espcrc2 ...
openaire   +3 more sources

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