Results 81 to 90 of about 2,131,360 (300)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
IEEE AccessEradicating Poverty in all its forms remains a key priority and a significant challenge in Tanzania. More than 50% of the population lives in multidimensional poverty, with urban poverty stagnating while rural poverty, though higher, is declining at a ...
Ngong'ho Bujiku Sende +2 more
doaj +1 more source
General fuzzy min-max neural network for clustering and classification [PDF]
, 2000 This paper describes a general fuzzy min-max (GFMM) neural network which is a generalization and extension of the fuzzy min-max clustering and classification algorithms of Simpson (1992, 1993).
Gabrys, Bogdan, Bargiela, Andrzej
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Clustering analysis of railway driving missions with niching [PDF]
, 2012 A wide number of applications requires classifying or grouping data into a set of categories or clusters. Most popular clustering techniques to achieve this objective are K-means clustering and hierarchical clustering.
Jaafar, Amine +2 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
An Overview of Co-Clustering via Matrix Factorization
IEEE Access, 2019 Co-clustering algorithms have been widely used for text clustering and gene expression through matrix factorization. In recent years, diverse co-clustering algorithms which group data points and features synchronously have shown their advantages over ...
Renjie Lin, Shiping Wang, Wenzhong Guo
doaj +1 more source
Extended Fuzzy Clustering Algorithms [PDF]
Fuzzy clustering is a widely applied method for obtaining fuzzy models from data. Ithas been applied successfully in various fields including finance and marketing.
Kaymak, U., Setnes, M.
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source