Results 81 to 90 of about 239,550 (307)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Identifying and Ranking of Best Influential Spreaders With Extended Clustering Coefficient Local Global Centrality Method

IEEE Access
The detection and ranking of influential nodes in complex networks are crucial for various practical applications such as identifying potential drug targets in protein-to-protein interaction networks, critical devices in communication networks, key ...
Mondikathi Chiranjeevi, V Sateeshkrishna Dhuli, Murali Krishna Enduri, Linga Reddy Cenkeramaddi   +3 more
doaj   +1 more source

Exponential domination, exponential independence, and the clustering coefficient

, 2017
This dissertation contains four research papers. The first two papers are about exponential domination in graphs, which is a variant of domination in graphs.
Jäger, Simon
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A Normalized Tree Index for identification of correlated clinical parameters in microarray data

, 2011
Martin C, Tauchen A, Becker A, Nattkemper TW. A Normalized Tree Index for identification of correlated clinical parameters in microarray data. BioData Mining.
Nattkemper, Tim Wilhelm ; https://orcid.org/, Nattkemper Tim W, Anika Tauchen, Tauchen, Annika, Tauchen Anika, Anke Becker, Martin, Christian, Martin Christian W, Becker Anke, Tim W Nattkemper, Becker, Anke, Christian W Martin   +11 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Clustering Coefficient Increasing Local Link Switching Algorithm

, 2014
This paper proposed a local link switching algorithm which effectively increases the clustering coefficient of a network while preserving the network node degree distributions.
Tsai, Yih-Jia
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Streamflow Prediction Using Complex Networks

Entropy
The reliable prediction of streamflow is crucial for various water resources, environmental, and ecosystem applications. The current study employs a complex networks-based approach for the prediction of streamflow.
Abdul Wajed Farhat, B. Deepthi, Bellie Sivakumar   +2 more
doaj   +1 more source

Identifying Influential Spreaders in Social Networks Via Normalized Local Structure Attributes

IEEE Access, 2018
In social networks, influential spreaders are those nodes that can spread information to a large number of nodes. Identifying influential spreaders is a major challenge for applications, such as information diffusion acceleration, epidemic outbreak ...
Xiaohui Zhao, Fang'ai Liu, Shuning Xing, Qianqian Wang   +3 more
doaj   +1 more source