Results 81 to 90 of about 242,831 (264)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

The clustering coefficient of a scale-free random graph

open access: yesDiscrete Applied Mathematics, 2011
17 pages ...
Nicole Eggemann, Steven D. Noble
openaire   +3 more sources

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Generalization of Clustering Coefficients to Signed Correlation Networks

open access: yesPLoS ONE, 2014
The recent interest in network analysis applications in personality psychology and psychopathology has put forward new methodological challenges. Personality and psychopathology networks are typically based on correlation matrices and therefore include both positive and negative edge signs.
COSTANTINI, GIULIO, PERUGINI, MARCO
openaire   +4 more sources

Topological Evolution and Prediction Method of Permeability in Fracture Networks

open access: yesApplied Sciences
Aiming to predict the evolution of fracture structures under stress conditions and the Permeability process of the fracture network, a damage evolution model reflecting the coupling mechanism between topological characteristics and mechanical responses ...
Juan Chen   +4 more
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Measuring the Clustering Strength of a Network via the Normalized Clustering Coefficient

open access: yesCoRR, 2019
In this paper, we propose a novel statistic of networks, the normalized clustering coefficient, which is a modified version of the clustering coefficient that is robust to network size, network density and degree heterogeneity under different network generative models.
Ting Li, Xianshi Yu, Bing-Yi Jing
openaire   +2 more sources

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