Results 71 to 80 of about 1,758,281 (314)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

IT Clusters as a Special Type of Industrial Clusters [PDF]

open access: yes
Economic and industrial clusters have become in the last years the object of a new economic theory that has proved important for regional and even national (Porter, 1990) development.
Catalin BOJA
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Clusters: Determinants and Effects [PDF]

open access: yes
This memorandum surveys the empirical literature about the effects and determinants of clusters. It finds that clusters generally lead to more innovations, knowledge spillovers, faster diffusion of technologies and knowledge, and competitive advantages ...
Alex Hoen
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Genetic divergence in brinjal (Solanummelongena L.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2015
Genetic divergence among 50 genotypes of brinjal for 16 characters was estimated using Mahalanobis D2 statistic. The genotypes were grouped into eight clusters on the basis of relative magnitude of D2 values.
Sadarunnisa S.,Reddy R.V.S.K.,Begum H.,Reddy T.D and Reddy P.N.
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Evaluation stages of digital potential of an innovation-active industrial cluster of the Arctic zone of Russia

open access: yesНаучно-технические ведомости СПбГПУ: Экономические науки, 2020
Formation and development of global information and economic society, digital economy and economy of the Arctic zone impose new requirements to opportunities and competitiveness of the states, regions, organizational and economic systems, clusters and ...
Babkin Aleksandr, Tashenova Larisa
doaj   +1 more source

Social Networks across Spatial Agglomerations: the Paradox of High-Tech Clusters. A Critical Revision of Clusters [PDF]

open access: yes
This paper analyzes a fundamental gap research in high-tech clusters surveying literature in a critical perspective: the paper evidenced the taken-for-granted assumption that knowledge spillovers (KS) are unique assets conveying flows of knowledge in ...
Jose-Luis Hervas-Oliver
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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