Results 11 to 20 of about 103,507 (289)
Impaired Chaperone-Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation. [PDF]
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Chen X +9 more
europepmc +2 more sources
Die CMA auf dem Prüfstand [PDF]
Der Beitrag möchte gern als Aufforderung zu einer wissenschaftlichen Diskussion über die Aufgabenschwerpunkte, nicht nur der CMA, sondern auch der ZMP und des Absatzfonds, verstanden werden.
Becker, Tilman
core +6 more sources
In several real-world applications in medical and control engineering, there are unsafe solutions whose evaluations involve inherent risk. This optimization setting is known as safe optimization and formulated as a specialized type of constrained optimization problem with constraints for safety functions. Safe optimization requires performing efficient
Kento Uchida +4 more
openaire +4 more sources
Discussant to Managerial Accounting Guidelines
paper presented at the CMA Symposium in Guelph, Ontario, Canada, ( 05 ...
Williams, John Joseph
core +7 more sources
Performance Evaluation of CMA-BJ V2.0 System for Precipitation Forecast in North China
To meet the requirement of numerical weather forecast for local severe convective weather, especially disastrous weather and extreme weather events, based on CMA-BJ V2.0 system, many works have been implemented, including increasing the model vertical ...
Zhang Shuting +6 more
doaj +1 more source
The influence of combustion temperature on alkali content of cattle manure ash
Cattle manure ash (CMA) is an industrial waste resulting from the burning of cow dung in power plants. The relationship between the alkali content of CMA and alkali aggregate reaction determines whether CMA can be used in cement based materials.
Shuguang Zhou +3 more
doaj +1 more source
Chaperone Mediated Autophagy Substrates and Components in Cancer
Chaperone-mediated autophagy (CMA) represents a specific way of lysosomal protein degradation and contrary to macro and microautophagy is independent of vesicles formation.
Javiera Rios +5 more
doaj +1 more source
The population size, i.e., the number of candidate solutions generated at each iteration, is the most critical strategy parameter in the covariance matrix adaptation evolution strategy, CMA-ES, which is one of the state-of-the-art search algorithms for black-box continuous optimization.
Kouhei Nishida, Youhei Akimoto
openaire +2 more sources
Based on the homogenized daily data of 2255 meteorological stations during the past 60 years from 1961 to 2020, the potential evapotranspiration was calculated using the revised FAO56 Penman–Monteith model, and then the annual AI (aridity index, the ...
Cunjie Zhang +6 more
doaj +1 more source
CONSTRUCTING GENDER IDENTITY THROUGH METAPHOR IN AMERICAN TRAP MUSIC [PDF]
American trap, as a contemporary, popular musical genre which depicts a society full of vice, drugs, sexual promiscuity and immorality, seems to have nothing in common with any type of tradition or norms and moral values, let alone patriarchal society ...
Dijana Jurčić, Lidija Mustapić
doaj +1 more source

