Results 71 to 80 of about 32,320 (220)

Statistically controlled identification of differentially expressed genes in one-to-one cell line comparisons of the CMAP database for drug repositioning

Journal of Translational Medicine, 2017
The Connectivity Map (CMAP) database, an important public data source for drug repositioning, archives gene expression profiles from cancer cell lines treated with and without bioactive small molecules.
Jun He, Haidan Yan, H. Cai, Xiangyu Li, Qingzhou Guan, Weicheng Zheng, Rou Chen, Hua-Ping Liu, Kai Song, Zheng Guo, Xianlong Wang   +10 more
semanticscholar   +1 more source

Muscle‐Specific Kinase Signaling and Its Therapeutic Potential

Muscle &Nerve, EarlyView.
ABSTRACT The function of the neuromuscular junction (NMJ) is compromised in many neuromuscular diseases (NMDs) such as autoimmune or congenital myasthenia gravis (MG), amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and muscular dystrophies.
Stine Marie Jensen, Dana L. E. Vergoossen, Maartje G. Huijbers   +2 more
wiley   +1 more source

Overlapping compounds/drugs identified from CMAP analysis.

, 2018
Overlapping compounds/drugs identified from CMAP analysis.
Mitsutaka Takada (5832344), Mai Fujimoto (5832338), Lili Mao (289583), Kouichi Hosomi (5832335), Kazutaka Ushio (5832341), Juran Kato (2093692)   +5 more
core   +1 more source

CMAP decrement as a potential diagnostic marker for ALS

Acta Neurologica Scandinavica, 2016
We previously reported that decrement of compound muscle action potential (CMAP) by repetitive nerve stimulation (RNS) was greater in the median nerves than in the ulnar nerves of patients with amyotrophic lateral sclerosis (ALS).
A. Mori, Satoshi Yamashita, M. Nakajima, Hiroko Hori, A. Tawara, Y. Matsuo, Y. Misumi, Yukio Ando   +7 more
semanticscholar   +1 more source

Pattern Differences of Small Hand Muscle Atrophy in Amyotrophic Lateral Sclerosis and Mimic Disorders

Chinese Medical Journal, 2016
Background: Amyotrophic lateral sclerosis (ALS) and some mimic disorders, such as distal-type cervical spondylotic amyotrophy (CSA), Hirayama disease (HD), and spinobulbar muscular atrophy (SBMA) may present with intrinsic hand muscle atrophy. This study
Jia Fang, Ming-Sheng Liu, Yu-Zhou Guan, Hua Du, Ben-Hong Li, Bo Cui, Qing-Yun Ding, Li-Ying Cui   +7 more
doaj   +1 more source

A Hybrid Rule‐Based and Large Language Model Artificial Intelligence System for Electrodiagnostic Reporting: Two‐Center Retrospective Evaluation

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Electrodiagnostic (EDX) studies comprise nerve conduction studies (NCS) and needle electromyography (EMG). However, EDX reporting is heterogeneous across laboratories and often requires time‐consuming documentation. We aimed to evaluate a hybrid rule‐based and constrained large language model (LLM) system that drafts EDX ...
Yesung Jung, Min Kyun Sohn, Ja Young Choi, Kang Hee Cho   +3 more
wiley   +1 more source

CMap 1.01: A comparative mapping application for the Internet

, 2009
CMap is a web-based tool for displaying and comparing maps of any type and from any species. A user can compare an unlimited number of maps, view pair-wise comparisons of known correspondences, and search for maps or for features by name, species, type ...
Stein, L. D., Youens-Clark, K., Faga, B. P., Yap, I. V., Ware, D. H.   +4 more
core   +1 more source

Exploring physics concepts among novice teachers through CMAP tools

, 2018
Concept maps are graphical tools for organising, elaborating and representing knowledge. Through Cmap tools software, it can be explored the understanding and the hierarchical structuring of physics concepts among novice teachers.
N. Suprapto, Suliyanah, B. K. Prahani, M. N. R. Jauhariyah, S. Admoko   +4 more
semanticscholar   +1 more source

Cyclo‐Polyproline: Chameleonic All‐Peptide Macrocycles With Induced‐Fit Host‐Guest Recognition

Angewandte Chemie, Volume 138, Issue 27, 1 July 2026.
Macrocycles served as the genesis of supramolecular chemistry, advancing synthetic, separation, and materials fields. Despite their utility, they typically lack synthetic control. This work establishes a robust platform for all‐peptide macrocycles capable of host‐guest complexation and chameleonic behavior.
Camilla Di Girolamo, Patricia C. Fleming, Caroline R. Kwawu, Amanda R. Guimarães, Jimmy Muldoon, Julia Bruno‐Colmenarez, Yannick Ortin, Michael R. Probert, Felipe Fantuzzi, Aniello Palma   +9 more
wiley   +2 more sources

The integral equation methods for the perturbed Helmholtz eigenvalue problems

International Journal of Mathematics and Mathematical Sciences, 2005
It is well known that the main difficulty in solving eigenvalue problems under shape deformation relates to the continuation of multiple eigenvalues of the unperturbed configuration.
Abdessatar Khelifi
doaj   +1 more source