Results 81 to 90 of about 15,154 (201)
ABSTRACT Introduction/Aims Critical illness polyneuropathy and/or myopathy (CIP/CIM) is a major cause of weakness in the intensive care unit (ICU). The availability of conventional electrodiagnostic testing may be limited. Alternative electrophysiologic methods, including the strength‐duration test (SDT) and the stimulus electrodiagnosis test (SET ...
José Roberto de Deus Macedo +5 more
wiley +1 more source
The additional files for the major revision of Cell lineage-resolved embryonic morphological map reveals novel signaling regulating cell fate and size asymmetry (https://www.researchsquare.com/article/rs-4664717/v1)
Zelin Li, Guoye Guan
openaire +1 more source
Revisiting the compound muscle action potential (CMAP)
The compound muscle action potential (CMAP) is among the first recorded waveforms in clinical neurography and one of the most common in clinical use. It is derived from the summated muscle fiber action potentials recorded from a surface electrode overlying the studied muscle following stimulation of the relevant motor nerve fibres innervating the ...
Paul E. Barkhaus +4 more
openaire +3 more sources
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
This study delineates the dynamic transcriptomic landscape of OLF across normal, immature, and mature stages via RNA‐seq. LTBP4 shows progressive downregulation and is validated in external datasets. Single‐cell and spatial transcriptomics identify fibroblasts as the cellular source.
Xiao Zhang +7 more
wiley +1 more source
mdashkezari/cmap-agent-paper: CMAP Agnet Paper
Reference repository for CMAP agent CMAP Agent document project. The paper introduces an agentic retrieval-augmented interface for dataset discovery, access, integration, and analysis on Simons CMAP data platform.
openaire +1 more source
Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos +46 more
wiley +1 more source
Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton +4 more
wiley +1 more source
ABSTRACT Digital twins serve as virtual replicas of physical systems. They can be used as a tool for engineering education by revealing the underlying principles behind unit operations. The project aimed to integrate digital twins into university engineering lab courses, complementing traditional methods by bridging the gap between experimentation and ...
Carles Troyano Ferré +5 more
wiley +1 more source
Unexpected Conduction Blocks in SORD‐Related Distal Motor Neuropathy: A Case Report
ABSTRACT Distal weakness requires an extensive differential diagnosis. In this case, conduction blocks indicated multifocal motor neuropathy, but immunotherapy proved ineffective. Ultimately, genetic testing revealed a sorbitol dehydrogenase mutation, highlighting the importance of combining electrophysiological findings with molecular studies in cases
Amiela Angeli Bucur +7 more
wiley +1 more source

