Results 91 to 100 of about 1,019 (146)

A genetically informed cross‐lagged twin study of the longitudinal association between addiction‐related behaviors and obesity

Addiction, EarlyView.
Abstract Background and aims Addiction‐related behaviors, such as loss of control eating (LOC), cigarette smoking and alcohol consumption, have been associated with high body mass index (BMI). This study aimed to assess genetic and environmental contributions to these associations over time.
Baiyu Qi, Heather M. Highland, Mariaelisa Graff, Cynthia M. Bulik, Soo Hyun Rhee, Michael C. Stallings, John K. Hewitt, Daniel E. Gustavson, Chandra A. Reynolds, Kari E. North, Melissa A. Munn‐Chernoff   +10 more
wiley   +1 more source

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Allergy, EarlyView.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud, Emil M. Pallesen, Ziao Zeng, Martin R. J. Namini, Chella Krishna Vadivel, Lise Mette Rahbek Gjerdrum, Lang Yan, Sana Ahmad, Lise M. Lindahl, Michael Bzorek, Maria R. Kamstrup, Saptaswa Dey, Sisse Rye Ostrowski, Erik Sørensen, Pia Rantakari, Charlotte Menne Bonefeld, Carsten Geisler, Anders Woetmann, Riitta Lahesmaa, Lars Iversen, Peter Wolf, Thomas Litman, Terkild B. Buus, Niels Ødum   +23 more
wiley   +1 more source

Triple Bottom Line (TBL) Perspective on the Business–Environment–Performance Nexus in an Emerging Market Economy

Business Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Sustainability has become a defining challenge for firms in emerging economies, where pressures to address environmental and social concerns increasingly intersect with the need to remain financially competitive. Yet many organizations struggle to show whether sustainability disclosures create measurable business value, particularly in complex
Li KaoDui, Maxwell Kongkuah, Ummar Faruk Saeed, Noha Alessa   +3 more
wiley   +1 more source

Molecular and clinical features of a Japanese medulloblastoma cohort: Subgroup‐specific prognostic stratification using economical/accessible diagnostic methods

Brain Pathology, EarlyView.
This study characterizes the molecular subgroup–specific features of a nationwide Japanese cohort comprising 242 medulloblastomas (MBs). Furthermore, we introduce SEE‐6‐CNA, a simple, cost‐effective, and FFPE‐compatible molecular test that is applicable to routine pathology samples and serves as a surrogate for risk stratification in non‐WNT/non‐SHH ...
Kohichi Go, Asako Katsuma, Ema Yoshioka, Tomoko Shofuda, Kohei Fukuoka, Koichi Ichimura, Yuko Matsushita, Yohei Mineharu, Yasuhide Makino, Takeshi Kawauchi, Atsushi Sasaki, Junko Hirato, Takeshi Inoue, Yoshinori Kodama, Masayuki Mano, Daisuke Kanematsu, Noriyuki Kijima, Naoki Kagawa, Dai Keino, Akitake Mukasa, Tomonari Suzuki, Koji Yoshimoto, Daisuke Kuga, Keishi Horiguchi, Shigeru Yamaguchi, Masayuki Kanamori, Kai Yamasaki, Kenichi Ishibashi, Takuya Akai, Masayoshi Yamaoka, Ryuji Ishizaki, Atsufumi Kawamura, Shigeo Ohba, Joji Ishida, Ryo Ando, Junya Fukai, Tomoru Miwa, Masazumi Fujii, Ai Muroi, Kuniaki Saito, Atsuko Harada, Yasuhiko Hayashi, Masahiro Nonaka, Young‐Soo Park, Yusuke Kobayashi, Tadashi Higuchi, Yosuke Miyairi, Kazuhisa Yoshifuji, Noriyoshi Takebe, Soichi Oya, Kosuke Nakajo, Mitsutoshi Nakada, Yoshiteru Nakano, Mizuki Kambara, Koji Adachi, Kazuhiro Tanaka, Hideo Nakamura, Yukihiko Sonoda, Ryuta Saito, Takafumi Wataya, Kazuhiko Kurozumi, Michael D. Taylor, Yoshitaka Narita, Soichiro Shibui, Hajime Arai, Hiroaki Sakamoto, Isao Date, Motoo Nagane, Ryo Nishikawa, Yoshiki Arakawa, Yonehiro Kanemura   +70 more
wiley   +1 more source

Repeated Exposure to Hydroperoxides of Linalool Induces Immunologically Verified Allergic Contact Dermatitis

Contact Dermatitis, EarlyView.
Patch testing and repeated use (ROAT) with Lin‐OOH revealed dose‐dependent reactions in sensitised individuals. Lin‐OOH 1.0% was the most reliable patch test concentration to confirm CA in our cohort. Skin biopsy gene expression analysis shows upregulation of IL1β, IL4, GATA3 and CCL22, confirming activation of immune pathways consistent with fragrance
Sofia Botvid, Niels Højsager Bennike, Jeanne Duus Johansen, Alexandra T. Seibel, Helen Vaher, Charlotte Menné Bonefeld, Aaron I. Moore, Niamh O'Boyle, Lina Hagvall   +8 more
wiley   +1 more source

Artificial Intelligence in Type 1 Diabetes Management: A Scoping Review of Randomised Controlled Trials

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Artificial intelligence is emerging in healthcare systems. In type 1 diabetes, AI‐enabled tools are increasingly used to support nutrition assessment and insulin decision‐making, yet their clinical utility and safety remain unclear. Methods The study aims to identify and map the evidence on the clinical utility of AI‐based diabetes ...
Yucen Wu, Jun Pang, Shaoyong Xu, Lalantha Leelarathna, Aaron M. Lett   +4 more
wiley   +1 more source

PEG-Lipid-PLGA Hybrid Particles for Targeted Delivery of Anti-Inflammatory Drugs. [PDF]

Pharmaceutics
Ismail J, Klepsch LC, Dahlke P, Tsarenko E, Vollrath A, Pretzel D, Jordan PM, Rezaei K, Czaplewska JA, Stumpf S, Beringer-Siemers B, Nischang I, Hoeppener S, Werz O, Schubert US.   +14 more
europepmc   +1 more source

Start(up) with purpose: How goal‐ and duty‐based purpose drive work engagement and performance in startups

European Management Review, EarlyView.
ABSTRACT Although organizational purpose (OP) has recently gained attention in entrepreneurship research, its motivational potential in startups remains underexplored, limiting the development of effective purpose‐driven strategies to enhance employee work engagement (WE) and startup performance.
Julien A. Nussbaum, Enya Henning, Paulin L. Ostrowski, Dominik K. Kanbach   +3 more
wiley   +1 more source

Relational and Contractual Governance in Auditor–Client Relationships: Effects on Value‐Added Auditing

International Journal of Auditing, EarlyView.
ABSTRACT Prior research examining value‐added auditing in auditor–client relationships is primarily based on the auditor's perspective. We extend this line of research by examining how governance patterns and clients' perceived risk of material misstatement and cognitive conflict are associated with the provision of value‐added audit services.
Ranjith Appuhami, Jing Jia, Zhongtian Li
wiley   +1 more source

Beyond Leadership Skills: The Conditional Impact of Self‐Directed Protean Career Orientation on Leader Identity Formation

International Journal of Training and Development, EarlyView.
ABSTRACT This study investigates how leadership skills contribute to leader identity formation through prosocial impact at work and how this process is shaped by self‐directed protean career orientation (PCO). Drawing on the identity‐development spiral model, we conceptualize consideration and initiating structure as core leadership skills and examine ...
Shohei Hayashi, Kohei Saito
wiley   +1 more source