Results 141 to 150 of about 125,744 (212)
Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein
The study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Babu Kanti Nath +7 more
wiley +1 more source
Targeting dCas9‐SunTag to a Susceptibility Gene Promoter Is Sufficient for CRISPR Interference
ABSTRACT Cassava production in sub‐Saharan Africa is severely impacted by diseases. Most pathogens require interaction with host susceptibility factors to complete their life cycles and cause disease. Targeted DNA methylation is an epigenetic strategy to alter gene expression in plants, and we previously reported that a zinc‐finger fused to DMS3 could ...
Zuh‐Jyh Daniel Lin +14 more
wiley +1 more source
Effect of data-collection method on reporting of common mental disorder symptoms and intimate partner violence in Zimbabwe: a cluster-randomized trial. [PDF]
Simms V +12 more
europepmc +1 more source
This study investigates how drawing process parameters affect the tribological behavior of AISI 304 steel sheet. Under lubricated conditions, increasing normal force, drawing speed, and countersamples roughness reduces the coefficient of friction by up to 21%.
Felipe de Souza Leal +6 more
wiley +1 more source
Assessment of cholesterol-HDL-glucose index in anticipating risk of cardiometabolic diseases: a comparative study with triglyceride-glucose index. [PDF]
Tang J, Wei S, Li Y, Zhou Y.
europepmc +1 more source
ABSTRACT Background Microscopic colitis (MC), comprising lymphocytic colitis (LC) and collagenous colitis (CC), is an inflammatory bowel disease with increasing incidence. MC etiopathogenesis remains unknown; however, altered colonic epithelial integrity may underlie uncontrolled luminal antigen passage, triggering immuno‐inflammatory responses ...
Danila Guagnozzi +18 more
wiley +1 more source
Plant‐based fermentation matrices significantly influence microbial diversity and species‐specific proteomic adaptations. The integration of MALDI‐TOF MS and 16S rRNA sequencing with physicochemical analyses allowed for a better understanding of the impact of specific fermentation products on differences in microbial diversity and spectral protein ...
Agnieszka Ludwiczak +8 more
wiley +1 more source
This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan +6 more
wiley +1 more source

