Results 151 to 160 of about 125,744 (212)

Reduced Proteasome Degradation of HSF‐1 Shifts Protein Stress Management With Age in Caenorhabditis elegans

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Ageing C. elegans prioritises chronic protein stress protection over acute stress response by coordinating HSF‐1 activity. Decreased PBS‐7 binding in aged worms reduces HSF‐1 degradation, enhancing its ability to upregulate protective factors against accumulating protein aggregates while simultaneously suppressing its activation under acute heat shock.
Hongwei Wang   +11 more
wiley   +1 more source

Reflections on Consciousness in Intensive Care

open access: yesActa Paediatrica, Volume 115, Issue 2, Page 275-284, February 2026.
ABSTRACT Evaluating consciousness in intensive care is pivotal to relieving suffering with analgesic or sedative drugs and in prognosis and diagnoses. The usual clinical perspective is to equate consciousness with responsiveness, assuming functional motor responses and sympathetic activity of the patient. Clinical diagnoses of coma may be wrong in more
Michael Broomé, Tiit Mathiesen
wiley   +1 more source

The PERISCOPE Cohort: A Retrospective Study of Clinicopathological and TRAF7 Genetic Findings in Intraneural Perineurioma

open access: yesEuropean Journal of Neurology, Volume 33, Issue 2, February 2026.
ABSTRACT Background Intraneural perineurioma (INP) is a rare, benign peripheral nerve sheath tumour that typically presents in adolescence or early adulthood as a slowly progressive, motor‐predominant mononeuropathy or plexopathy. Although its clinicoradiological and histopathological features are well characterised, the genetic basis remains ...
Eduardo Boiteux Uchôa Cavalcanti   +7 more
wiley   +1 more source

Maternal perinatal mental health and associated factors during the first postpartum year from a longitudinal birth cohort study in Rahim Yar Khan, Pakistan. [PDF]

open access: yesGlob Ment Health (Camb)
Datta RR   +10 more
europepmc   +1 more source

Glycoside Hydrolase CaGH17‐12 Contributes to Phytophthora Blight Resistance by Activating the Production of Reactive Oxygen Species and Jasmonic Acid Signalling in Pepper

open access: yesMolecular Plant Pathology, Volume 27, Issue 2, February 2026.
Glycoside hydrolase 17 family gene CaGH17‐12 contributes to P. capsici resistance by degrading pathogen‐derived β‐glucans and generating β‐glucan oligosaccharides, thereby triggering downstream JA signalling and ROS‐mediated defence responses. ABSTRACT Glycoside hydrolase family 17 (GH17) plays a critical role in degrading pathogen cell walls and is ...
Fengqing Cheng   +10 more
wiley   +1 more source

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