Results 1 to 10 of about 102,317 (247)
Blood, 2021 Patients with chronic myeloid leukemia in chronic phase (CML-CP) resistant or intolerant to ≥2 tyrosine kinase inhibitors (TKIs) are at high risk of experiencing poor outcomes due to disease biology and inadequate efficacy and/or safety of current ...
D. Réa +25 more
semanticscholar +1 more source
Metabolic alterations mediated by STAT3 promotes drug persistence in CML
Leukemia, 2021 Leukemic stem cells (LSCs) can acquire non-mutational resistance following drug treatment leading to therapeutic failure and relapse. However, oncogene-independent mechanisms of drug persistence in LSCs are incompletely understood, which is the primary ...
S. Patel +23 more
semanticscholar +1 more source
CML: Evolution and design [PDF]
Journal of Cheminformatics, 2011 A retrospective view of the design and evolution of Chemical Markup Language (CML) is presented by its original authors.
Murray-Rust, P, Rzepa, HS
openaire +6 more sources
Nature Communications, 2021 Building construction causes large material-related emissions which present a serious decarbonization challenge. Here, the authors show that the building material sector could halve emissions by increasing efficiency until 2060 but even then its ...
Xiaoyang Zhong +9 more
doaj +1 more source
Blood Advances, 2020 In an attempt to identify novel markers and immunological targets in leukemic stem cells (LSCs) in acute myeloid leukemia (AML) and chronic myeloid leukemia (CML), we screened bone marrow (BM) samples from patients with AML (n = 274) or CML (n = 97) and ...
H. Herrmann +18 more
semanticscholar +1 more source
Forecasting worldwide empty container availability with machine learning techniques
Journal of Shipping and Trade, 2022 Due to imbalances in the global transport of containerised goods, liner shipping companies go to great lengths to match the regional supply and demand for empty containers by transporting equipment from surplus to deficit regions.
Christoph Martius +4 more
doaj +1 more source
Electric vehicle batteries alone could satisfy short-term grid storage demand by as early as 2030
Nature Communications, 2023 Renewable energy and electric vehicles will be required for the energy transition, but the global electric vehicle battery capacity available for grid storage is not constrained.
Chengjian Xu +6 more
doaj +1 more source
Environmental DNA, 2021 The application of eDNA techniques for the detection, monitoring, and conservation of biodiversity holds great promise. While many studies apply eDNA techniques in aquatic systems to determine the presence or absence of a given species, using eDNA for ...
Krijn B. Trimbos +6 more
doaj +1 more source
A Comparison Between Global Nutrient Retention Models for Freshwater Systems
Frontiers in Water, 2022 Against the backdrop of increasing agricultural production, population, and freshwater/coastal eutrophication, studies are aiming to understand the behavior of nitrogen (N) and phosphorus (P) in the global freshwater system.
Jinhui Zhou +5 more
doaj +1 more source
Fine-resolution global maps of root biomass carbon colonized by arbuscular and ectomycorrhizal fungi
Scientific Data, 2023 Despite the recognized importance of mycorrhizal associations in ecosystem functioning, the actual abundance patterns of mycorrhizal fungi belowground are still unknown.
Milagros Barceló +2 more
doaj +1 more source