Results 1 to 10 of about 195,243 (312)
Nature Communications, 2021 Building construction causes large material-related emissions which present a serious decarbonization challenge. Here, the authors show that the building material sector could halve emissions by increasing efficiency until 2060 but even then its ...
Xiaoyang Zhong +9 more
doaj +1 more source
The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. [PDF]
, 2020 The endosteal bone marrow niche and vascular endothelial cells provide sanctuaries for leukemic cells. In murine chronic myeloid leukemia (CML) CD44 on leukemia cells and E-selectin on bone marrow endothelium are essential mediators for the engraftment ...
Aggoune, D. +17 more
core +2 more sources
Forecasting worldwide empty container availability with machine learning techniques
Journal of Shipping and Trade, 2022 Due to imbalances in the global transport of containerised goods, liner shipping companies go to great lengths to match the regional supply and demand for empty containers by transporting equipment from surplus to deficit regions.
Christoph Martius +4 more
doaj +1 more source
Electric vehicle batteries alone could satisfy short-term grid storage demand by as early as 2030
Nature Communications, 2023 Renewable energy and electric vehicles will be required for the energy transition, but the global electric vehicle battery capacity available for grid storage is not constrained.
Chengjian Xu +6 more
doaj +1 more source
Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells [PDF]
, 2016 Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at risk for relapse, and additional approaches to deplete CML LSC are needed to enhance the ...
Agarwal, Puneet +9 more
core +1 more source
Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia [PDF]
, 2014 Chronic myeloid leukemia (CML) is a stem cell (SC) neoplasm characterized by the BCR/ABL1 oncogene. Although mechanisms of BCR/ABL1-induced transformation are well-defined, little is known about effector-molecules contributing to malignant expansion and ...
Bilban, Martin +15 more
core +1 more source
Environmental DNA, 2021 The application of eDNA techniques for the detection, monitoring, and conservation of biodiversity holds great promise. While many studies apply eDNA techniques in aquatic systems to determine the presence or absence of a given species, using eDNA for ...
Krijn B. Trimbos +6 more
doaj +1 more source
MTSS1 is a critical epigenetically regulated tumor suppressor in CML [PDF]
, 2015 Chronic myeloid leukemia (CML) is driven by malignant stem cells that can persist despite therapy. We have identified Metastasis suppressor 1 (Mtss1/MIM) to be downregulated in hematopoietic stem and progenitor cells from leukemic transgenic SCLtTA/Bcr ...
Braunschweig, T. +18 more
core +1 more source
Conditional maximum likelihood timing recovery [PDF]
, 1999 The conditional maximum likelihood (CML) principle, well known in the context of sensor array processing, is applied to the problem of timing recovery. A new self-noise free CML-based timing error detector is derived.
Riba Sagarra, Jaume +1 more
core +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source