Results 41 to 50 of about 216,439 (378)
Conditional maximum likelihood timing recovery [PDF]
The conditional maximum likelihood (CML) principle, well known in the context of sensor array processing, is applied to the problem of timing recovery. A new self-noise free CML-based timing error detector is derived.
Riba Sagarra, Jaume+1 more
core +1 more source
We describe the COMPASS Modelling Language (CML), which is used to model large-scale Systems of Systems and the contracts that bind them together. The language can be used to document the interfaces to constituent systems using formal, precise, and verifiable specifications including preconditions, postconditions, and invariants.
Jim Woodcock+4 more
openaire +2 more sources
Genotyping by sequencing for estimating relative abundances of diatom taxa in mock communities
Background Diatoms are present in all waters and are highly sensitive to pollution gradients. Therefore, they are ideal bioindicators for water quality assessment.
Ozan Çiftçi+5 more
doaj +1 more source
Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML
Increasing evidence suggests that the immune system affects prognosis of chronic myeloid leukemia (CML), but the detailed immunological composition of the leukemia bone marrow (BM) microenvironment is unknown.
O. Brück+12 more
semanticscholar +1 more source
Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms and therapeutic options [PDF]
The onset of global epigenetic changes in chromatin that drive tumor proliferation and heterogeneity is a hallmark of many forms cancer. Identifying the epigenetic mechanisms that govern these changes and developing therapeutic approaches to modulate ...
Koschmieder, Steffen, Vetrie, David
core +1 more source
Chronic myeloid leukemia (CML) is a chronic disease resulting in myeloid cell expansion through expression of the BCR-ABL1 fusion transcript. Tyrosine kinase inhibitors (TKI) have significantly increased survival of patients with CML, and deep responders
Walid Warda+16 more
semanticscholar +1 more source
CML: the commonKADS conceptual modelling language [PDF]
We present a structured language for the specification of knowledge models according to the CommonKADS methodology. This language is called CML (Conceptual Modelling Language) and provides both a structured textual notation and a diagrammatic notation ...
Akkermans, J.M.+5 more
core +2 more sources
Evaluation of Imatinib adherence in chronic myeloid leukemia patients in Babylon Province, Iraq
Background: Chronic myeloid leukemia is a clonal myeloproliferative neoplasm that results in proliferation, mainly of granulocytic components. Resulting from t(9;22) with fusion oncogen BCR-ABL1 which has uninhibited tyrosine kinase activity.
Athmar Kadhim Gatea+2 more
doaj +1 more source
Understanding leukemia heterogeneity is critical for the development of curative treatments as the failure to eliminate therapy-persistent leukemic stem cells (LSCs) may result in disease relapse.
Rebecca Warfvinge+13 more
semanticscholar +1 more source
Inhibition of MDR1 does not sensitize primitive chronic myeloid leukemia CD34+ cells to imatinib [PDF]
<p><b>Objective:</b> To investigate the interaction of imatinib mesylate (IM) with the clinically relevant adenosine triphosphate-binding cassette efflux transporter MDR1 (ABCB1) in cells from patients with chronic myeloid leukemia (CML)
Hatziieremia, S.+4 more
core +1 more source