Results 171 to 180 of about 63,222 (303)

Strategic organisational improvising: Designing flexibility through planned incompleteness

open access: yesEuropean Management Review, EarlyView.
Abstract Traditional perspectives on strategic planning are often grounded in relatively static, overly detailed assumptions and frameworks about futures. Strategic organisational improvising is a critical process for organisations charting a way through complex, rapidly changing environments.
António Cunha Meneses Abrantes   +2 more
wiley   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

open access: yesThe FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester   +11 more
wiley   +1 more source

Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance

open access: yesThe FEBS Journal, EarlyView.
Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley   +1 more source

Hydrothermal origin of metabolic phosphorylation

open access: yesThe FEBS Journal, EarlyView.
Serpentinizing hydrothermal vents are candidate sites for biochemical origins. They generate extremely reducing conditions, depositing phosphite (HPO32−) and transition metals, including palladium, in the native (zero‐valent) state. Schlikker et al.
Manon L. Schlikker   +5 more
wiley   +1 more source

Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Pathway in High-Risk Lymphocytic Acute Myocarditis. [PDF]

open access: yesJACC Adv
Ammirati E   +29 more
europepmc   +1 more source

On the simulation and design of manycore CMPs.

open access: yes, 2015
The progression of Moore’s Law has resulted in both embedded and performance computing systems which use an ever increasing number of processing cores integrated in a single chip. Commercial systems are now available which provide hundreds of cores, and academics have proposed architectures for up to 1024 cores.
openaire   +2 more sources

Brand Equity and Debt Diversification

open access: yesFinancial Management, EarlyView.
ABSTRACT This study examines how brand equity influences the diversity of firms’ debt structures. We propose that brand equity, by signaling larger and more stable future cash flows and greater product market awareness, alters the fundamental trade‐offs that drive optimal debt type diversity.
David C. Mauer   +2 more
wiley   +1 more source

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