Results 151 to 160 of about 282,628 (342)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A Creative Approach to Isometries Integrating Geogebra and Italc with ‘Paper And Pencil’ Environments

open access: yesJETEN, 2015
Creativity is recognized nowadays as a basic skill. However, the educational system fails in promoting their development. On the other hand, a growing acknowledgement of the importance of geometry emerges.
Artur Coelho, Isabel Cabrita
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Data Quality Monitoring and Performance Studies of the Resistive Plate Chamber Detector at the CMS Experiment at LHC.

open access: yes, 2010
The CMS detector is a sophisticated and massive system: 7 different detector technologies, a high number of front-end electronic channels (10^7) , an input rate of 10^9 interactions per second, a trigger able to reduce the frequency by a factor 10^5, and
Cimmino, Anna
core  

First results and prospects in B physics at CMS

open access: yes, 2011
The first results in b physics obtained by the CMS collaboration from the data collected in pp collisions at 7 TeV at the LHC. In particular, results are reported on heavy quarkoniun production (J/ψ) and Y), and on inclusive b jet production cross ...
LIGABUE, FRANCO, CMS collaboration
core   +1 more source

Analysis environments for CMS

open access: yesJournal of Physics: Conference Series, 2008
The CMS offline software suite uses a layered approach to provide several different environments suitable for a wide range of analysis styles. At the heart of all the environments is the ROOT-based event data model file format. The simplest environment uses 'bare' ROOT to read files directly, without the use of any CMS-specific supporting libraries ...
Jones, C. D., Luca, L., Hegner, B.
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Upgrade of the CMS muon system with triple-GEM detectors

open access: yes, 2014
The CMS collaboration considers upgrading the muon forward region which is particularly affected by the high-luminosity conditions at the LHC. The proposal involves Gas Electron Multiplier (GEM) chambers, which are able to handle the extreme particle ...
Vitulo, P.   +4 more
core   +1 more source

Los procesos de titulización de activos: Comentarios al precedente de observancia obligatoria emitido por la superintendencia del mercado de valores

open access: yesThēmis, 2022
Recientemente, en el Perú, la SMV ha emitido un Precedente de Observancia Obligatoria en el que se ha puesto en cuestionamiento algunos aspectos referentes a dos fideicomisos de titulización.
Miguel Antonio Viale Leo   +1 more
doaj  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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