Results 51 to 60 of about 570,811 (281)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
POLYMORPHIC VARIANTS OF SUNFLOWER RFL-PPR GENES AS MOLECULAR GENETIC MARKERS
Труды по прикладной ботанике, генетике и селекции, 2018 A sample of 131 sunflower lines from VIR genetic collection which differed for the ability to suppression of the CMS phenotype was studied using molecular markers specific for the CMS PET1 associated mitochondrial locus orfH522 and Rf1 nuclear gene, and ...
I. N. Anisimova +5 more
doaj +1 more source
Heavy flavor Production and Interactions in Relativistic Heavy-Ion Collisions in CMS Experiment
, 2016 This paper presents the CMS measurements of quarkonia and open heavy flavor production in \pp, \pPb, and \PbPb collisions at \sqrtsnn = 2.76 and 5.02 TeV. A brief outlook of the near-future CMS heavy flavor physics analyses is provided at the end.Comment:
Xie, Wei
core +1 more source
A new Slow Control and Run Initialization Byte-wise Environment (SCRIBE) for the quality control of mass-produced CMS GEM detectors [PDF]
, 2016 The CMS collaboration aims at improving the muon trigger and tracking performance at the HL-LHC by installing new Gas Electron Multiplier (GEM) chambers in the endcaps of the CMS experiment.
Colafranceschi, S.
core +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Archeomatica, 2016 The National Archeological Museum of Reggio Calabria (MArRC) – which is dedicated to the history of the Magna Graecia and the culture of its people - is one of the twenty big italian museums - has recently undergone a major renovation; this renovation ...
Carmelo Malacrino +3 more
doaj
Detector and Event Visualization with SketchUp at the CMS Experiment
, 2013 We have created 3D models of the CMS detector and particle collision events in SketchUp, a 3D modelling program. SketchUp provides a Ruby API which we use to interface with the CMS Detector Description to create 3D models of the CMS detector.
McCauley, Thomas, Sakuma, Tai
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source