Results 71 to 80 of about 91,518 (261)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Accelerating the CM method [PDF]
LMS Journal of Computation and Mathematics, 2012 AbstractGiven a prime q and a negative discriminant D, the CM method constructs an elliptic curve E/Fq by obtaining a root of the Hilbert class polynomial HD(X) modulo q. We consider an approach based on a decomposition of the ring class field defined by HD, which we adapt to a CRT setting. This yields two algorithms, each of which obtains a root of HD
openaire +3 more sources
Engineering Analysis of CMS Casing
Механика машин, механизмов и материалов, 2014 In the article the methodological requirements that are indispensable for the implementation of construction documents for the production and operation of developed structures and facilities in order to support the transition of products into commodities
L.V. Larchenkov +2 more
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A clinical comparison of high dose and low dose of Suxamethonium
Journal of College of Medical Sciences-Nepal, 2014 Background: Suxamethonium having its rapid onset and short duration of action makes this drug unique amongst the neuromuscular blocking drugs described so far.
RK Yadav, PC Majhi, D Tiwari
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Journal of Physics: Conference Series, 2008 The CMS offline software suite uses a layered approach to provide several different environments suitable for a wide range of analysis styles. At the heart of all the environments is the ROOT-based event data model file format. The simplest environment uses 'bare' ROOT to read files directly, without the use of any CMS-specific supporting libraries ...
Jones, C. D., Luca, L., Hegner, B.
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JETEN, 2015 Creativity is recognized nowadays as a basic skill. However, the educational system fails in promoting their development. On the other hand, a growing acknowledgement of the importance of geometry emerges.
Artur Coelho, Isabel Cabrita
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source