Results 81 to 90 of about 95,205 (262)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Engineering Analysis of CMS Casing

open access: yesМеханика машин, механизмов и материалов, 2014
In the article the methodological requirements that are indispensable for the implementation of construction documents for the production and operation of developed structures and facilities in order to support the transition of products into commodities
L.V. Larchenkov   +2 more
doaj  

A clinical comparison of high dose and low dose of Suxamethonium

open access: yesJournal of College of Medical Sciences-Nepal, 2014
Background: Suxamethonium having its rapid onset and short duration of action makes this drug unique amongst the neuromuscular blocking drugs described so far.
RK Yadav, PC Majhi, D Tiwari
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

On the rank of CM-Type [PDF]

open access: yesNagoya Mathematical Journal, 1985
In the present note, we prove that every simple CM-type is non-degenerate (i.e. the rank is maximal) if the dimension of corresponding abelian varieties is a prime. This follows directly from the argument of Tankeev [5], in which he has treated the 5-dimensional case.Recently, S. G. Tankeev and K. A.
openaire   +2 more sources

A Creative Approach to Isometries Integrating Geogebra and Italc with ‘Paper And Pencil’ Environments

open access: yesJETEN, 2015
Creativity is recognized nowadays as a basic skill. However, the educational system fails in promoting their development. On the other hand, a growing acknowledgement of the importance of geometry emerges.
Artur Coelho, Isabel Cabrita
doaj  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Luminosity measurement at CMS [PDF]

open access: yesProceedings of Technology and Instrumentation in Particle Physics 2014 — PoS(TIPP2014), 2015
The measurement of the luminosity delivered by the LHC is pivotal for several key physics analyses. During the first three years of running, tremendous steps forward have been made in the comprehension of the subtleties related to luminosity monitoring and calibration, which led to an unprecedented accuracy at a hadron collider.
openaire   +3 more sources

Research on a CMS protocol for the substation control layer

open access: yesZhejiang dianli
To achieve a domestically developed alternative to the manufacturing message specification (MMS) as the core communication technology for the substation control layer, the State Grid Corporation of China has established the communication message ...
SUN Zhijia   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy