Results 61 to 70 of about 95,205 (262)
Sistemas Gestores de Contenido (CMS). La solución ideal en la Web
Ingenius: Revista de Ciencia y Tecnología, 2008 Sistemas Gestores de Contenido (CMS).
Rodolfo Bojorque
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Mathematics, 2019 A new approach to solve the compressible Navier-Stokes equations in cylindrical co-ordinates using Geometric Algebra is proposed. This work was recently initiated by corresponding author of this current work, and in contrast due to a now complete ...
Terry E. Moschandreou, Keith C. Afas
doaj +1 more source
The efects of heterosis of the sorghum hybrids F1 based on cytoplasmic male sterility
Зерновое хозяйство России, 2020 Currently, the development of highly productive sorghum hybrids with a high content of the main nutritional components in grain is of great relevance.
O. P. Kibalnik +5 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Труды по прикладной ботанике, генетике и селекции, 2019 Background. In breeding work, it is necessary to take into account such an important feature as male sterility of the hybrids obtained. If a plant has visually visible anthers and pollen, the quality of the pollen grains themselves may be low.
O. N. Voronova, V. A. Gavrilova
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Analysis of security CMS platforms by vulnerability scanners
Journal of Computer Sciences Institute, 2020 Subject of security the most popular CMS platforms has been undertaken in the following thesis. There were introduced fundamental informations about subject CMS platforms and vulnerability scanners utilised to research.
Patryk Zamościński, Grzegorz Kozieł
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Journal of Comparative Effectiveness ResearchAim: Diabetic foot ulcers (DFUs) are often hard to heal and may require advanced treatment with cellular, acellular and matrix-like products (CAMPs). This retrospective cohort study examines the Medicare feefor- service population to compare clinical ...
Brad Marcinek +6 more
doaj +1 more source