Results 91 to 100 of about 95,205 (262)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Los procesos de titulización de activos: Comentarios al precedente de observancia obligatoria emitido por la superintendencia del mercado de valores

open access: yesThēmis, 2022
Recientemente, en el Perú, la SMV ha emitido un Precedente de Observancia Obligatoria en el que se ha puesto en cuestionamiento algunos aspectos referentes a dos fideicomisos de titulización.
Miguel Antonio Viale Leo   +1 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

UNEP/CMS Raptors MoU

open access: yesПернатые хищники и их охрана, 2018
The Raptors MoU is implemented via an Action Plan that promotes an internationally co-ordinated approach to the conservation of African-Eurasian birds of prey, with the overall aim being to return and maintain these species in Favourable Conservation ...
Nick P. Williams
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Anglikan (İngiliz) misyoner teşkilatlar

open access: yesBozok Üniversitesi İlahiyat Fakültesi Dergisi, 2016
Anglikan Kilisesi, İngiltere’nin resmi kilisesidir. Bu kilise dünya üzerinde her yere misyoner teşkilatları sayesinde yayılmıştır. Başlıca İngiliz misyoner teşkilatlar SPCK, USPG ve CMS’dir.
Resul Çatalbaş
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Optimization Of Digital Marketing Utilization Based on E-Commerce to Enhance Sales and Marketing

open access: yesJurnal Sisfokom
This study aims to develop and optimize digital marketing strategies through an e-commerce–based system for the Charming Charlotte accessories business in order to enhance sales effectiveness and competitive advantage. The problems identified include the
Adinda Dwi Larasati, Anita Diana
doaj   +1 more source

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