Results 111 to 120 of about 576,615 (299)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Anglikan (İngiliz) misyoner teşkilatlar
Bozok Üniversitesi İlahiyat Fakültesi Dergisi, 2016 Anglikan Kilisesi, İngiltere’nin resmi kilisesidir. Bu kilise dünya üzerinde her yere misyoner teşkilatları sayesinde yayılmıştır. Başlıca İngiliz misyoner teşkilatlar SPCK, USPG ve CMS’dir.
Resul Çatalbaş
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Nuclear Physics A, 2013 AbstractThe CMS collaboration has used a data set of 1 billion PbPb collisions at the LHC to study the behavior of strongly interacting matter at high temperature. In this Paper, we present selected recent highlights from this effort, with a particular emphasis on results related to the hydrodynamic expansion of the produced matter, the energy loss of ...
openaire +3 more sources
Research on a CMS protocol for the substation control layer
Zhejiang dianliTo achieve a domestically developed alternative to the manufacturing message specification （MMS） as the core communication technology for the substation control layer， the State Grid Corporation of China has established the communication message ...
SUN Zhijia +3 more
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
The CMS Experiment: Status and First Results
, 2010 After nearly two decades of design, construction and commissioning, the CMS detector was operated with colliding LHC proton beams for the first time in November 2009.
Mulders, Martijn
core
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source