Light modulated cnidocyte discharge predates the origins of eyes in Cnidaria [PDF]
Ecology and Evolution, 2021 Complex biological traits often originate by integrating previously separate parts, but the organismal functions of these precursors are challenging to infer.
Natasha Picciani +5 more
doaj +13 more sources
Functional analysis in a model sea anemone reveals phylogenetic complexity and a role in cnidocyte discharge of DEG/ENaC ion channels [PDF]
Communications Biology, 2023 Phylogenetic analyses demonstrate a remarkable variety of the degenerin/epithelial Na+ channel (DEG/ENaC) superfamily in Cnidaria and discern an unexpected role for a proton-sensitive DEG/ENaC in N. vectensis cnidocyte discharge.
Jose Maria Aguilar-Camacho +5 more
doaj +8 more sources
Cnidocyte discharge is regulated by light and opsin-mediated phototransduction [PDF]
BMC Biology, 2012 Background Cnidocytes, the eponymous cell type of the Cnidaria, facilitate both sensory and secretory functions and are among the most complex animal cell types known.
Plachetzki David C +2 more
doaj +14 more sources
Doublecortin-like kinase is required for cnidocyte development in Nematostella vectensis [PDF]
Neural DevelopmentThe complex morphology of neurons requires precise control of their microtubule cytoskeleton. This is achieved by microtubule-associated proteins (MAPs) that regulate the assembly and stability of microtubules, and transport of molecules and vesicles ...
Johanna E. M. Kraus +4 more
doaj +9 more sources
Chemical Compositions and Experimental and Computational Modeling of the Anticancer Effects of Cnidocyte Venoms of Jellyfish Cassiopea andromeda and Catostylus mosaicus on Human Adenocarcinoma A549 Cells [PDF]
Marine Drugs, 2023 Nowadays, major attention is being paid to curing different types of cancers and is focused on natural resources, including oceans and marine environments.
Afshin Zare +13 more
doaj +6 more sources
PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis [PDF]
EvoDevo, 2017 Background Pax genes are a family of conserved transcription factors that regulate many aspects of developmental morphogenesis, notably the development of ectodermal sensory structures including eyes.
Leslie S. Babonis, Mark Q. Martindale
doaj +7 more sources
Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis [PDF]
Nature Communications, 2022 The evolutionary point where chromatin modifier function integrated into regulation of specific cell types is unclear. In the cnidarian Nematostella vectensis, the authors here show that lysine specific demethylase Lsd1 is developmentally regulated and ...
James M. Gahan +4 more
doaj +4 more sources
Cnidarian hair cell development illuminates an ancient role for the class IV POU transcription factor in defining mechanoreceptor identity [PDF]
eLife, 2021 Although specialized mechanosensory cells are found across animal phylogeny, early evolutionary histories of mechanoreceptor development remain enigmatic. Cnidaria (e.g.
Ethan Ozment +6 more
doaj +6 more sources
An ancient pan-cnidarian microRNA regulates stinging capsule biogenesis in Nematostella vectensis
Cell Reports, 2023 Summary: An ancient evolutionary innovation of a novel cell type, the stinging cell (cnidocyte), appeared >600 million years ago in the phylum Cnidaria (sea anemones, corals, hydroids, and jellyfish).
Arie Fridrich +7 more
doaj +2 more sources
A developmental role for the chromatin-regulating CoREST complex in the cnidarian Nematostella vectensis. [PDF]
BMC Biol, 2022 Background: Chromatin-modifying proteins are key players in the regulation of development and cell differentiation in animals. Most chromatin modifiers, however, predate the evolution of animal multicellularity, and how they gained new functions and ...
Gahan JM +3 more
europepmc +3 more sources