Light modulated cnidocyte discharge predates the origins of eyes in Cnidaria. [PDF]
Ecol Evol, 2021 Complex biological traits like eyes often evolve by combining previously separate parts that originally served other organismal functions. Here, we investigate eye evolution in Cnidaria by testing whether an ancient role for light sensitivity was to modulate cnidocyte discharge, even before eyes originated.
Picciani N +5 more
europepmc +16 more sources
Functional analysis in a model sea anemone reveals phylogenetic complexity and a role in cnidocyte discharge of DEG/ENaC ion channels. [PDF]
Commun Biol, 2023 AbstractIon channels of the DEG/ENaC family share a similar structure but serve strikingly diverse biological functions, such as Na+ reabsorption, mechanosensing, proton-sensing, chemosensing and cell-cell communication via neuropeptides. This functional diversity raises the question of the ancient function of DEG/ENaCs. Using an extensive phylogenetic
Aguilar-Camacho JM +5 more
europepmc +9 more sources
Cnidocyte discharge is regulated by light and opsin-mediated phototransduction [PDF]
BMC Biology, 2012 Cnidocytes, the eponymous cell type of the Cnidaria, facilitate both sensory and secretory functions and are among the most complex animal cell types known. In addition to their structural complexity, cnidocytes display complex sensory attributes, integrating both chemical and mechanical cues from the environment into their discharge behavior.
Plachetzki, David C +2 more
core +15 more sources
Doublecortin-like kinase is required for cnidocyte development in Nematostella vectensis. [PDF]
Neural DevAbstractThe complex morphology of neurons requires precise control of their microtubule cytoskeleton. This is achieved by microtubule-associated proteins (MAPs) that regulate the assembly and stability of microtubules, and transport of molecules and vesicles along them.
Kraus JEM +4 more
europepmc +9 more sources
Chemical Compositions and Experimental and Computational Modeling of the Anticancer Effects of Cnidocyte Venoms of Jellyfish Cassiopea andromeda and Catostylus mosaicus on Human Adenocarcinoma A549 Cells. [PDF]
Mar Drugs, 2023 Nowadays, major attention is being paid to curing different types of cancers and is focused on natural resources, including oceans and marine environments. Jellyfish are marine animals with the ability to utilize their venom in order to both feed and defend. Prior studies have displayed the anticancer capabilities of various jellyfish.
Zare A +13 more
europepmc +7 more sources
Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis. [PDF]
Nat Commun, 2022 Chromatin regulation is a key process in development but its contribution to the evolution of animals is largely unexplored. Chromatin is regulated by a diverse set of proteins, which themselves are tightly regulated in a cell/tissue-specific manner ...
Gahan JM +4 more
europepmc +4 more sources
Cnidarian hair cell development illuminates an ancient role for the class IV POU transcription factor in defining mechanoreceptor identity. [PDF]
Elife, 2021 Although specialized mechanosensory cells are found across animal phylogeny, early evolutionary histories of mechanoreceptor development remain enigmatic. Cnidaria (e.g.
Ozment E +6 more
europepmc +6 more sources
Grouped vesicles from the Middle East. [PDF]
J Dtsch Dermatol GesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 2, Page 212-217, February 2025.
Baaske KM, Sunderkötter C, Montag A.
europepmc +5 more sources
Mechanisms of cnidocyte development in the moon jellyfish Aurelia. [PDF]
Evol Dev, 2019 Stinging cells called cnidocytes are a defining trait of the cnidarians (sea anemones, corals, jellyfish, and their relatives). In hydrozoan cnidarians such as Hydra, cnidocytes develop from interstitial stem cells set aside in the ectoderm. It is less clear how cnidocytes develop outside the Hydrozoa, as other cnidarians appear to lack interstitial ...
Gold DA +5 more
europepmc +8 more sources
A developmental role for the chromatin-regulating CoREST complex in the cnidarian Nematostella vectensis. [PDF]
BMC Biol, 2022 Background: Chromatin-modifying proteins are key players in the regulation of development and cell differentiation in animals. Most chromatin modifiers, however, predate the evolution of animal multicellularity, and how they gained new functions and ...
Gahan JM +3 more
europepmc +3 more sources