Results 31 to 40 of about 68,640 (273)

Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells

Cells, 2021
C-type natriuretic peptide (CNP) is the major natriuretic peptide of the central nervous system and acts via its selective guanylyl cyclase-B (GC-B) receptor to regulate cGMP production in neurons, astrocytes and endothelial cells.
Jacob T. Regan, Samantha M. Mirczuk, Christopher J. Scudder, Emily Stacey, Sabah Khan, Michael Worwood, Torinn Powles, J. Sebastian Dennis-Beron, Matthew Ginley-Hidinger, Imelda M. McGonnell, Holger A. Volk, Rhiannon Strickland, Michael S. Tivers, Charlotte Lawson, Victoria J. Lipscomb, Robert C. Fowkes   +15 more
doaj   +1 more source

Protective Effects of C-Type Natriuretic Peptide on Linear Growth and Articular Cartilage Integrity in a Mouse Model of Inflammatory Arthritis [PDF]

, 2014
Objective: The C-type natriuretic peptide (CNP) signaling pathway is a major contributor to postnatal skeletal growth in humans. This study was undertaken to investigate whether CNP signaling could prevent growth delay and cartilage damage in an animal ...
Bartels, Cynthia F, Bükülmez, Hülya, Haqqi, Tariq M, Khan, Fozia, Murakami, Shunichi, Ortiz-Lopez, Adriana, Sattar, Abdus, Warman, Matthew L   +7 more
core   +1 more source

Foramen magnum stenosis and midface hypoplasia in C-type natriuretic peptide-deficient rats and restoration by the administration of human C-type natriuretic peptide with 53 amino acids.

PLoS ONE, 2019
C-type natriuretic peptide (CNP)-knockout (KO) rats exhibit impaired skeletal growth, with long bones shorter than those in wild-type (WT) rats. This study compared craniofacial morphology in the CNP-KO rat with that in the Spontaneous Dwarf Rat (SDR), a
Takafumi Yotsumoto, Naomi Morozumi, Mayumi Furuya, Toshihito Fujii, Keisho Hirota, Yohei Ueda, Kazumasa Nakao, Shigeki Yamanaka, Kazunori Yoshikiyo, Sayaka Yoshida, Tomonari Nishimura, Yasuyuki Abe, Toshimasa Jindo, Hiroyuki Ogasawara, Akihiro Yasoda   +14 more
doaj   +1 more source

Socio-Ecological Significance and Anthropogenic Threats to <i>Berlinia</i> (Sol. ex Hook.f., 1849) and <i>Isoberlinia</i> (Stapf, 1911) Species in Côte d'Ivoire. [PDF]

Ecol Evol
Species of the genera Isoberlinia and Berlinia are threatened with extinction due to the abusive exploitation of their distribution area including various forms of use. However, their availability and socio‐cultural importance are little known and/or neglected.
Karim SG, Bakary S, Koné NGA.
europepmc   +2 more sources

Glial βii spectrin contributes to paranode formation and maintenance [PDF]

, 2018
Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous ...
Benusa, Savannah D., Chang, Kae Jiun, Dupree, Jeffrey L., Galiano, Mauricio Raul, Griggs, Ryan B., Huang, Claire Yu Mei, Liu, Yanhong, Rasband, Matthew N., Susuki, Keiichiro, Tsai, Chang Ru, Yermakov, Leonid M., Zhang, Chuansheng, Zollinger, Daniel R.   +12 more
core   +1 more source

Quantum Hall conductance of two-terminal graphene devices [PDF]

, 2008
Measurement and theory of the two-terminal conductance of monolayer and bilayer graphene in the quantum Hall regime are compared. We examine features of conductance as a function of gate voltage that allow monolayer, bilayer, and gapped samples to be ...
C. M. Marcus, C. W. J. Beenakker, D. A. Abanin, J. R. Williams, L. DiCarlo, L. S. Levitov, T. A. Driscoll   +6 more
core   +3 more sources

C-Type Natriuretic Peptide Pre-Treatment Improves Maturation Rate of Goat Oocytes by Maintaining Transzonal Projections, Spindle Morphology, and Mitochondrial Function

Animals, 2023
C-type natriuretic peptide (CNP) is a peptide molecule naturally found in follicles and can be used to extend meiotic resumption and enhance the potential for oocytes to develop.
Rui Xu, Menghao Pan, Lu Yin, Yiqian Zhang, Yaju Tang, Sihai Lu, Yan Gao, Qiang Wei, Bin Han, Baohua Ma   +9 more
doaj   +1 more source

CNP, Cardiac Natriuretic Peptide? [PDF]

Endocrinology, 2004
Identifying the primary target tissues and functions of natriuretic peptides has at times proven difficult. For example, the second natriuretic peptide was initially identified in porcine brain extracts (1). Therefore, it was logically named brain natriuretic peptide (BNP).
openaire   +1 more source

Uncovering oligodendrocyte enhancers that control Cnp expression

Human Molecular Genetics, 2023
Abstract Oligodendrocytes (OLs) produce myelin sheaths around axons in the central nervous system (CNS). Myelin accelerates the propagation of action potentials along axons and supports the integrity of axons. Impaired myelination has been linked to neurological and neuropsychiatric disorders.
Fan, Chuandong, An, Hongjoo, Kim, Dongkyeong, Park, Yungki   +3 more
openaire   +2 more sources

Evidence of feedback regulation of C-type natriuretic peptide during Vosoritide therapy in Achondroplasia

Scientific Reports, 2021
Evidence from genetic disorders of CNP signalling suggests that plasma concentrations of CNP are subject to feedback regulation. In subjects with Achondroplasia (Ach), CNP intracellular activity is suppressed and plasma concentrations are raised but the ...
Timothy C. R. Prickett, Eric A. Espiner, Melita Irving, Carlos Bacino, John A. Phillips, Ravi Savarirayan, Jonathan R. S. Day, Elena Fisheleva, Kevin Larimore, Ming Liang Chan, George S. Jeha   +10 more
doaj   +1 more source