Results 51 to 60 of about 23,430 (264)

Extracellular PHF-tau modulates astrocyte mitochondrial dynamics and mediates neuronal connectivity

Translational Neurodegeneration
Background Tau is an intracellular protein that plays a crucial role in stabilizing microtubules. However, it can aggregate into various forms under pathological conditions and be secreted into the brain parenchyma.
Valentin Zufferey, Aatmika Barve, Enea Parietti, Luc Belinga, Audrey Bringaud, Yvan Varisco, Kerstin Fabbri, Francesca Capotosti, Paola Bezzi, Nicole Déglon, Pierre Marquet, Nicolas Preitner, Kevin Richetin   +12 more
doaj   +1 more source

Therapeutic effect of C-type natriuretic peptide on persistent pain in a rat knee arthritis model

Journal of Orthopaedic Surgery, 2023
Background Intra-articular injection of C-type natriuretic peptide (CNP) at the acute inflammatory stage suppressed fibrotic changes in the infrapatellar fat pad (IFP), articular cartilage degeneration, and persistent pain in a monoiodoacetic acid (MIA ...
Shoichi Hasegawa, Jae-Sung An, Jun Hino, Yusuke Amano, Yusuke Nakagawa, Kazumasa Miyatake, Hiroki Katagiri, Tomomasa Nakamura, Ichiro Sekiya, Hideyuki Koga, Kunikazu Tsuji   +10 more
doaj   +1 more source

Approval of support_EGCG CNPs

, 2022
Approval of support on EGCG CNPs ...
openaire   +1 more source

Effects of CNP-53 on body weight, length, craniofacial morphology, and foramen magnum size in CNP-KO rats.

, 2019
(A) Body weight and length, (B) relative lengths of craniofacial morphology to WT rats, (C) relative size of foramen magnum to WT rats. WT, WT rats which received vehicle; CNP-KO, CNP-KO rats which received vehicle; CNP-KO + CNP, CNP-KO rats which ...
Yasuyuki Abe (276178), Kazumasa Nakao (4994402), Shigeki Yamanaka (4994396), Keisho Hirota (4994384), Toshihito Fujii (4994393), Tomonari Nishimura (3049353), Akihiro Yasoda (4112263), Takafumi Yotsumoto (4994390), Yohei Ueda (4994381), Naomi Morozumi (4994399), Mayumi Furuya (2794603), Kazunori Yoshikiyo (5774975), Sayaka Yoshida (3406), Toshimasa Jindo (4994387), Hiroyuki Ogasawara (6729206)   +14 more
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Plasma concentrations of C-nartiuretic peptide and endothelin-1 in women with essential hypertension which suffered vascular complication when inherent of different variants of angiotensin II type 1 receptor gene

Zaporožskij Medicinskij Žurnal, 2013
Plasma level of C-natriuretic peptide (CNP) and endothelin-1 (ET-1) was performed among postmenopausal age’s women, patients with essential hypertension (EH), which complicated myocardial infarction or cerebral stroke, who live in Vinnitsa region, with ...
S. V. Franchuk, O. L. Starzhynska
doaj   +1 more source

Head and neck morphology of MPS VII, MPS VII-GUSB, MPS VII/SAP-CNP and MPS VII-GUSB/SAP-CNP mice.

, 2022
(A) Three-dimensional reconstructed images of the skulls of 12-week-old MPS VII, MPS VII-GUSB, MPS VII/SAP-CNP and MPS VII-GUSB/SAP-CNP mice. (B) Linear measurements for analysis of normal mouse skulls (left). Linear measurements from 12-week-old MPS VII,
Kazumasa Nakao (4994402), Mariko Yamamoto Kawai (14100769), Shigeki Yamanaka (4994396), Yohei Ueda (4994381), Shizuko Fukuhara (9937019), Toshihito Fujii (4994393), Ichiro Yamauchi (4112260), Takuma Watanabe (4059760), Marina Kashiwagi (14100766), Takafumi Yamashita (5774984), Kazuhisa Bessho (65293)   +10 more
core   +1 more source

Electric Field‐Induced Hole‐ and Electron‐Type Flat Bands in Twisted Double Bilayer Graphene

Advanced Electronic Materials, EarlyView.
The electronic structure of twisted double bilayer graphene is visualized using angle‐resolved photoemission spectroscopy with micrometer spatial resolution at twists of 3.1∘$^\circ$ and 6.0∘$^\circ$ as a function of gate voltage. Tunable hybridization effects and flat band formation occurs between valence and conduction band states due to a finite ...
Zhihao Jiang, Dongkyu Lee, Alfred J. H. Jones, Youngju Park, Paulina Majchrzak, Kimberly Hsieh, Chakradhar Sahoo, Thomas S. Nielsen, Kenji Watanabe, Takashi Taniguchi, Philip Hofmann, Yong P. Chen, Jeil Jung, Søren Ulstrup   +13 more
wiley   +1 more source

Circulating C-Type Natriuretic Peptide (CNP) Rescues Chondrodysplastic CNP Knockout Mice from Their Impaired Skeletal Growth and Early Death

, 2010
C-type natriuretic peptide (CNP) is a potent stimulator of endochondral bone growth through a subtype of membranous guanylyl cyclase receptor, GC-B. Although its two cognate natriuretic peptides, ANP and BNP, are cardiac hormones produced from heart, CNP
Hiroshi Arai, Masako Miura, Naotestu Kanamoto, Yasato Komatsu, Eri Kondo, Kazuwa Nakao, Naohisa Tamura, Akihiro Yasoda, Toshihito Fujii, Masashi Mukoyama, Tetsuro Yoshioka, Takuo Nambu   +11 more
core   +1 more source

Multifactor Risk Stratification for Post‐Transplant Alcohol Relapse Using Abstinence, Psychosocial, and Socioeconomic Factors

Annals of Gastroenterological Surgery, EarlyView.
Alcohol relapse after liver transplantation is difficult to predict using abstinence duration alone. We developed a multifactor model integrating abstinence duration, psychosocial risk (SIPAT), and socioeconomic context (AUC 0.70). This approach may support individualized risk assessment and tailored follow‐up intensity; external validation is needed ...
Ayato Obana, Garren Montgomery, Miho Akabane, Matthew Hamilton, Navdeep Singh, Musab Alebrahim, Austin Schenk, Sylvester Black, Kenneth Washburn, Khalid Mumtaz   +9 more
wiley   +1 more source