Results 31 to 40 of about 23,430 (264)

Oromucosal Administration of a Cannabidiol-Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain. [PDF]

Eur J Pain
ABSTRACT Background Chronic neuropathic pain (CNP) involves complex interactions between resident and peripheral immune cells, as well as modulation of the endocannabinoid system. Cannabis‐based products have emerged as promising therapeutic options, but their effects on immune cells remain unclear.
Campos RMP, Conde L, Aguiar A, Sampaio L, de Melo Reis RA, Pimentel-Coelho PM.   +5 more
europepmc   +2 more sources

Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells

Cells, 2021
C-type natriuretic peptide (CNP) is the major natriuretic peptide of the central nervous system and acts via its selective guanylyl cyclase-B (GC-B) receptor to regulate cGMP production in neurons, astrocytes and endothelial cells.
Jacob T. Regan, Samantha M. Mirczuk, Christopher J. Scudder, Emily Stacey, Sabah Khan, Michael Worwood, Torinn Powles, J. Sebastian Dennis-Beron, Matthew Ginley-Hidinger, Imelda M. McGonnell, Holger A. Volk, Rhiannon Strickland, Michael S. Tivers, Charlotte Lawson, Victoria J. Lipscomb, Robert C. Fowkes   +15 more
doaj   +1 more source

Evidence of feedback regulation of C-type natriuretic peptide during Vosoritide therapy in Achondroplasia

Scientific Reports, 2021
Evidence from genetic disorders of CNP signalling suggests that plasma concentrations of CNP are subject to feedback regulation. In subjects with Achondroplasia (Ach), CNP intracellular activity is suppressed and plasma concentrations are raised but the ...
Timothy C. R. Prickett, Eric A. Espiner, Melita Irving, Carlos Bacino, John A. Phillips, Ravi Savarirayan, Jonathan R. S. Day, Elena Fisheleva, Kevin Larimore, Ming Liang Chan, George S. Jeha   +10 more
doaj   +1 more source

Foramen magnum stenosis and midface hypoplasia in C-type natriuretic peptide-deficient rats and restoration by the administration of human C-type natriuretic peptide with 53 amino acids.

PLoS ONE, 2019
C-type natriuretic peptide (CNP)-knockout (KO) rats exhibit impaired skeletal growth, with long bones shorter than those in wild-type (WT) rats. This study compared craniofacial morphology in the CNP-KO rat with that in the Spontaneous Dwarf Rat (SDR), a
Takafumi Yotsumoto, Naomi Morozumi, Mayumi Furuya, Toshihito Fujii, Keisho Hirota, Yohei Ueda, Kazumasa Nakao, Shigeki Yamanaka, Kazunori Yoshikiyo, Sayaka Yoshida, Tomonari Nishimura, Yasuyuki Abe, Toshimasa Jindo, Hiroyuki Ogasawara, Akihiro Yasoda   +14 more
doaj   +1 more source

Effective Connectivity in Spinal Cord Injury-Induced Neuropathic Pain

Sensors, 2022
Aim: The aim of this study was to differentiate the effects of spinal cord injury (SCI) and central neuropathic pain (CNP) on effective connectivity during motor imagery of legs, where CNP is typically experienced.
Radha Kumari, Mohammed Jarjees, Ioana Susnoschi-Luca, Mariel Purcell, Aleksandra Vučković   +4 more
doaj   +1 more source

Efficiency of C-type natriuretic peptide on improvement of Iraqi local ram's epididymal sperms

Open Veterinary Journal
Background: Fertility plays great role in animal reproduction since high quality semen improves sheep industry reproduction. The current worldwide data revealed the closely related of CNP to reproductive function of rams. Aims: Evaluation the effect of
Massar Saeb Khadim, Nazih Wayes Zaid
doaj   +1 more source

Association between migraine and risk of ocular motor cranial nerve palsy

Scientific Reports, 2022
To assess association between migraines and development of ocular motor cranial nerve palsy (CNP) and finding risk factors using the National Sample Cohort database from the Korea National Health Insurance Service.
Soolienah Rhiu, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh   +4 more
doaj   +1 more source

Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide

, 2004
Background: Ischemia/reperfusion (I/R) injury complicates myocardial infarction and stroke by exacerbating tissue damage and increasing risk of mortality.
Ramona Scotl, Hobbs, Adrian, Ahluwalia, Amrita, Foster, Paul, Hobbs, A., Phd Amrita Ahluwalia, Foster, P., Adrian Hobbs, Phd Paul Foster, Scotland, R., Prescott, Craig, Scotland, Ramona, Ahluwalia, A., Phd Craig Prescott, Natriuretic Peptide, Prescott, C.   +15 more
core   +1 more source

C-Type Natriuretic Peptide Pre-Treatment Improves Maturation Rate of Goat Oocytes by Maintaining Transzonal Projections, Spindle Morphology, and Mitochondrial Function

Animals, 2023
C-type natriuretic peptide (CNP) is a peptide molecule naturally found in follicles and can be used to extend meiotic resumption and enhance the potential for oocytes to develop.
Rui Xu, Menghao Pan, Lu Yin, Yiqian Zhang, Yaju Tang, Sihai Lu, Yan Gao, Qiang Wei, Bin Han, Baohua Ma   +9 more
doaj   +1 more source

In vitro and in vivo evaluation of cerium oxide nanoparticles in respiratory syncytial virus infection

Bioactive Materials, 2023
Respiratory syncytial virus (RSV) is the most common cause of viral bronchiolitis among children worldwide, yet there is no vaccine for RSV disease.
Akhil Patel, Jessica Kosanovich, Sameera Sansare, Sricharani Balmuri, Vinayak Sant, Kerry M. Empey, Shilpa Sant   +6 more
doaj   +1 more source