Results 191 to 200 of about 502,861 (219)

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Global Burden and Temporal Trends of Brain and Central Nervous System Tumors in Children and Adolescents: A Systematic Analysis for the Global Burden of Disease Study 2021. [PDF]

Cancer Innov
Feng Z, Su Y, Yang L, Deng K, Wang J, Zhang J, Liu F, Wang D, Liang Y, Wang W, Qiu X, Jiang T, Tian Y, Liu H.   +13 more
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Psychometric Properties of Instruments to Assess Movement Disorders in People With Intellectual Disabilities Using Antipsychotics: A Systematic Literature Review. [PDF]

J Appl Res Intellect Disabil
Hoekstra-van Duijn MLD, Wissing MBG, den Haan B, Beumer S, Maes-Festen DAM.   +4 more
europepmc   +1 more source

[Chemotherapy-related central nervous system injury in children with acute lymphoblastic leukemia: research progress]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Wang L, Shen NP, Shi SY, DU M, Yan JQ, Jiang Y.   +5 more
europepmc   +1 more source

Hyaluronidase-enhanced delivery in gene therapy and regenerative medicine for improved vector, cell, and cargo access. [PDF]

Front Drug Deliv
Sewell PE, Jensen C.
europepmc   +1 more source

Novel targeted therapies for central nervous system involvement in chronic lymphocytic leukemia: A systematic review. [PDF]

Ther Adv Hematol
Al-Mashdali AF, Abdelraof MO, Mukhtar RM, Mohamed SF.   +3 more
europepmc   +1 more source

Case Report: Central nervous system infiltration after allogeneic hematopoietic stem cell transplantation in high-risk myelodysplastic neoplasms. [PDF]

Front Oncol
Shi L, Zhu J, Wang Y, Wu D, Miao M, Zhou H, Gong H.   +6 more
europepmc   +1 more source

Clinical Nurse Specialists' Journey From Novice to Expert-A Systematic Mixed-Method Review. [PDF]

Scand J Caring Sci
Imeläinen SM, Kvist TA, Wright MMM, Jokiniemi KS.   +3 more
europepmc   +1 more source

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The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

Cell Metabolism, 2021
Susanna M Hofmann, Andreas Blutke, Diego Perez-Tilve   +2 more
exaly