Results 181 to 190 of about 502,861 (219)

Is Hemorrhagic Demyelinating Lesions of Central Nervous System a Spectrum?

Caspian Journal of Neurological Sciences, 2019
Abdorreza Naser Moghadasi, Hamidreza Hatamian   +1 more
doaj  

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

Correction to 'Advanced Lymphoblastic Lymphoma, NOS in Leukaemic Phase Presenting With Sudden and Fatal CNS Haemorrhage'. [PDF]

Case Rep Pathol
europepmc   +1 more source

Acute Neurological Manifestations in COVID-19 Are Associated With Complement Activation and Glia-Promoted Neuroinflammation. [PDF]

J Med Virol
Freitas NL, Gomes YCP, Nogueira FCS, Echevarria-Lima J, Deus JVC, Brandão CO, Soares CN, Silva MTT, Espíndola OM.   +8 more
europepmc   +1 more source

Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals

Advanced Science, EarlyView.
A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu, Sultan Mahmud, Mali Halac, Asif Iftekhar Omi, Domenica Sofia Baez Rodas, Jeremiasz Dados, Chaojun Cheng, Anyu Jiang, Cameron Wallace, Anvi Singh, Erin Patrick, Baibhab Chatterjee, Shriya Srinivasan, Adam Khalifa   +13 more
wiley   +1 more source

Do Brain Extracellular Fluid Concentrations Predict PET-Inferred Receptor Occupancy in Human CNS? A Mechanistic Model-Based Analysis of Dopamine D2 Receptor Ligands. [PDF]

Clin Pharmacol Ther
Budda D, van Hasselt JGC, de Lange ECM.
europepmc   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Hypothetical applications of MR-guided focused ultrasound in central nervous system tuberculosis: blood-brain barrier disruption, granulomatous lesion modulation, targeted drug delivery, and immune microenvironment reprogramming. [PDF]

Ann Med Surg (Lond)
Beniwal SS, Mwaanga C, Jassim M, Rawat A, Dahiya P, Ribeiro da Costa REA, Pandey A, Ali ASM, Moncada J, Mateen SSA, Mishra A.   +10 more
europepmc   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Literature review of pediatric Erdheim-Chester disease (ECD) and mixed histiocytosis (Langerhans cell histiocytosis/ECD). [PDF]

Ann Transl Med
Imashuku S.
europepmc   +1 more source