Results 11 to 20 of about 162,890 (205)

Sources of CNS tumor heterogeneity [PDF]

Oncoscience, 2014
Central nervous system tumors are marked with high intra- and inter-tumoral heterogeneity. For instance, an integrative large scale gene expression study performed in 2010 revealed 4 subtypes glioblastoma multiforme (GBM) with differential responses to treatment and prognosis [1].
Fuyi, Chen, Albert, Becker, Joseph, LoTurco   +2 more
openaire   +2 more sources

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev, Ganeshan, Dhakshinamoorthy, Lubner, Meghan G., Menias, Christine O., Pickhardt, Perry J., Ramalingam, Preetha, Sandrasegaran, Kumaresan   +6 more
core   +1 more source

APPLICATION OF PHOTODYNAMIC THERAPY IN TREATMENT OF MALIGNANT NEOPLASMS OF THE CENTRAL NERVOUS SYSTEM

Паёми Сино, 2020
World literature data dedicated to the problem of application of photodynamic therapy (PDT) in the neurooncology has been studied and analyzed, and also the prospects for development and improvement of surgical treatment for malignant neoplasms of CNS ...
A.A. SUFIANOV, D.A. MURZAEVA, I.S. SHELYAGIN, R.A. SUFIANOV   +3 more
doaj   +1 more source

Molecular identification of CNS NB-FOXR2, CNS EFT-CIC, CNS HGNET-MN1 and CNS HGNET-BCOR pediatric brain tumors using tumor-specific signature genes

Acta Neuropathologica Communications, 2020
Four molecular types of rare central nervous system (CNS) tumors have been recently identified by gene methylation profiling: CNS Neuroblastoma with FOXR2 activation (CNS NB-FOXR2), CNS Ewing Sarcoma Family Tumor with CIC alteration (CNS EFT-CIC), CNS ...
Maria Łastowska, Joanna Trubicka, Anna Sobocińska, Bartosz Wojtas, Magdalena Niemira, Anna Szałkowska, Adam Krętowski, Agnieszka Karkucińska-Więckowska, Magdalena Kaleta, Maria Ejmont, Marta Perek-Polnik, Bożenna Dembowska-Bagińska, Wiesława Grajkowska, Ewa Matyja   +13 more
doaj   +1 more source

Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts

Acta Neuropathologica Communications, 2019
The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this issue, we investigated the prognostic impact
Toru Umehara, Hideyuki Arita, Ema Yoshioka, Tomoko Shofuda, Daisuke Kanematsu, Manabu Kinoshita, Yoshinori Kodama, Masayuki Mano, Naoki Kagawa, Yasunori Fujimoto, Yoshiko Okita, Masahiro Nonaka, Kosuke Nakajo, Takehiro Uda, Naohiro Tsuyuguchi, Junya Fukai, Koji Fujita, Daisuke Sakamoto, Kanji Mori, Haruhiko Kishima, Yonehiro Kanemura   +20 more
doaj   +1 more source

Citrate in Pediatric CNS Tumors? [PDF]

American Journal of Neuroradiology, 2008
In a subset of in vivo MR spectra acquired from pediatric brain tumors, we have observed an unassigned peak. The goal of this study was to determine the molecule of origin, and the prevalence and concentration of this chemical in various pediatric brain tumors.Single-voxel point-resolved spectroscopy (PRESS) spectra from 85 patients with brain tumors ...
Z A, Seymour, A, Panigrahy, J L, Finlay, M D, Nelson, S, Blüml   +4 more
openaire   +2 more sources

Intracranial mesenchymal tumor with (novel) COX14::PTEN rearrangement

Acta Neuropathologica Communications, 2023
Mesenchymal tumors of the central nervous system (CNS) include numerous entities, with different pathological features and biological behavior. Mesenchymal non-meningothelial tumors are rare and comprise neoplasms that are exclusive to the CNS or show ...
Antonio d’Amati, Francesca Gianno, Luciana Scuccimarri, Michele Lastilla, Raffaella Messina, Francesco Signorelli, Domenico Sergio Zimatore, Sabina Barresi, Evelina Miele, Rita Alaggio, Sabrina Rossi, Eugenio Maiorano, Giuseppe Ingravallo, Felice Giangaspero, Manila Antonelli   +14 more
doaj   +1 more source

Editorial: Spatiotemporal heterogeneity in CNS tumors [PDF]

Frontiers in Immunology
Syed M. Faisal, Vidhya M. Ravi, Jason M. Miska   +2 more
doaj   +2 more sources

Topical issues of the clinic of primary brain tumors

Медицинский совет, 2019
The article is devoted to the issue of clinical and neurological features of primary brain tumors (PBT). PBT account for 2% of the total number of human tumors. PBT represent an urgent social problem, causing disability and mortality.
T. I. Ashkhatsava, M. Yu. Tatarinova, L. M. Kogoniya, D. R. Naskhletashvili   +3 more
doaj   +1 more source

NECESSITY FOR A CUSTOMIZED NGS PANEL FOR ACCURATE DIAGNOSIS AND TARGETED THERAPIES IN PEDIATRIC GLIAL TUMORS

Hematology, Transfusion and Cell Therapy, 2021
Objective: Pediatric glial tumors comprise wide range pathologies which may mimic histomorphological features of each other's but generally have very diverse disease course. WHO Classification of Tumors of Central Nervous System (2016 and 2021) points to
Ayça Erşen Danyeli, Cengiz Yakıcıer, Bahattin Tanrıkulu, Cengiz Canpolat, M. Memet Özek   +4 more
doaj   +1 more source