Results 71 to 80 of about 162,890 (205)

Complete response to temozolomide in chronic lymphocytic leukemia

Clinical Case Reports, 2017
Key Clinical Message We report a case of incidentally diagnosed chronic lymphocytic leukemia (CLL) in a patient with glioblastoma, which responded completely following standard treatment of the glioblastoma with temozolomide and cranial irradiation.
Archana Rao, Nisha Ramani, Robert Stoppacher, Thomas Coyle   +3 more
doaj   +1 more source

Polo-Like Kinase 4 (PLK4) Is Overexpressed in Central Nervous System Neuroblastoma (CNS-NB)

Bioengineering, 2018
Neuroblastoma (NB) is the most common extracranial solid tumor in pediatrics, with rare occurrences of primary and metastatic tumors in the central nervous system (CNS).
Anders W. Bailey, Amreena Suri, Pauline M. Chou, Tatiana Pundy, Samantha Gadd, Stacey L. Raimondi, Tadanori Tomita, Simone Treiger Sredni   +7 more
doaj   +1 more source

GBM radiosensitizers: dead in the water…or just the beginning? [PDF]

, 2017
The finding that most GBMs recur either near or within the primary site after radiotherapy has fueled great interest in the development of radiosensitizers to enhance local control.
Bindra, Ranjit S., Chalmers, Anthony J., Dewhirst, Mark, Evans, Sydney   +3 more
core   +1 more source

EXPERIENCE IN USING IMMUNOHISTOCHEMICAL METHOD IN DIFFERENTIAL DIAGNOSIS OF CENTRAL NERVOUS SYSTEM TUMORS

Сибирский онкологический журнал, 2016
The purpose of the study was to evaluate the nosological structure of central nervous system (CNS) tumors and the role of immunohistochemical assay in verification of their histogenesis.Material and methods.
А. P. Nadeev, V. А. Zhukova, М. А. Kozyaev, М. А. Travin, К. Е. Yatsenko   +4 more
doaj  

Fermented mistletoe extract as a multimodal antitumoral agent in gliomas [PDF]

, 2012
In Europe, commercially available extracts from the white-berry mistletoe (Viscum album L.) are widely used as a complementary cancer therapy. Mistletoe lectins have been identified as main active components and exhibit cytotoxic effects as well as ...
Harter, Patrick Nikolaus, Mittelbronn, Michel Guy André, Naumann, Ulrike, Podlech, Oliver, Pöschel, Simone   +4 more
core   +2 more sources

DNA methylation-based classification of central nervous system tumours. [PDF]

, 2018
Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-
Aronica, Eleonora, Becker, Albert, Benner, Axel, Beschorner, Rudi, Bewerunge-Hudler, Melanie, Bjerkvig, Rolf, Braczynski, Anne K, Brehmer, Stefanie, Brück, Wolfgang, Calaminus, Gabriele, Capper, David, Chavez, Lukas, Coras, Roland, Cryan, Jane, Deckert, Martina, Dohmen, Hildegard, Driever, Pablo Hernáiz, Engel, Nils W, Farrell, Michael, Fischer, Roger, Fleischhack, Gudrun, Frank, Stephan, Frühwald, Michael C, Garvalov, Boyan K, Geisenberger, Christoph, Giangaspero, Felice, Gnekow, Astrid, Gottardo, Nicholas G, Haberler, Christine, Hans, Volkmar, Hansford, Jordan R, Harter, Patrick N, Hench, Jürgen, Heppner, Frank, Hewer, Ekkehard, Hofer, Silvia, Hovestadt, Volker, Huang, Kristin, Hänggi, Daniel, Hölsken, Annett, Jones, Chris, Jones, David TW, Jouvet, Anne, Kannan, Kasthuri, Keohane, Catherine, Ketter, Ralf, Khatib, Ziad, Koch, Arend, Koelsche, Christian, Kohlhof, Patricia, Kramm, Christof M, Kratz, Annekathrin, Kristensen, Bjarne W, Kulozik, Andreas, Lechner, Matt, Lindenberg, Kerstin, Lohmann, Dietmar, Lopes, Beatriz, Mawrin, Christian, Milde, Till, Monoranu, Camelia-Maria, Mueller, Wolf, Mühleisen, Helmut, Müller, Hermann L, Olar, Adriana, Pages, Melanie, Pajtler, Kristian W, Perry, Arie, Plate, Karl H, Pohl, Ute, Preusser, Matthias, Prinz, Marco, Reuss, David E, Rodriguez, Fausto J, Rozsnoki, Stephanie, Rushing, Elisabeth, Rutkowski, Stefan, Sahm, Felix, Scheurlen, Wolfram, Schick, Matthias, Schittenhelm, Jens, Schrimpf, Daniel, Schweizer, Leonille, Seiz-Rosenhagen, Marcel, Selt, Florian, Serrano, Jonathan, Sill, Martin, Staszewski, Ori, Stichel, Damian, Sturm, Dominik, Temming, Petra, Tippelt, Stephan, Tsirigos, Aristotelis, Varlet, Pascale, von Hoff, Katja, Wani, Khalida, Wefers, Annika K, Witt, Hendrik, Witt, Olaf, Zapatka, Marc   +99 more
core   +1 more source

First-line therapy in HER2 positive metastatic breast cancer. Is the mosaic fully completed or are we missing additional pieces? [PDF]

, 2016
The discovery of human epidermal growth factor receptor 2 (HER2) and its role in the biology of breast cancer and the subsequent development of HER2-targeted therapies, have dramatically improved clinical outcomes for women with early-stage and advanced ...
Cognetti F., Fabi A., Malaguti P., Vari S.   +3 more
core   +2 more sources

Identifying tumor type and cell type-specific gene expression alterations in pediatric central nervous system tumors

Nature Communications
Central nervous system (CNS) tumors are the leading cause of pediatric cancer death, and these patients have an increased risk for developing secondary neoplasms.
Min Kyung Lee, Nasim Azizgolshani, Joshua A. Shapiro, Lananh N. Nguyen, Fred W. Kolling, George J. Zanazzi, Hildreth Robert Frost, Brock C. Christensen   +7 more
doaj   +1 more source

Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy. [PDF]

, 2019
Glioma is one of the most refractory types of brain tumor. Accurate tumor boundary identification and complete resection of the tumor are essential for glioma removal during brain surgery.
Alfano, Robert R, Cheng, Gangge, Liu, Cheng-Hui, Shi, Lingyan, Wang, Kai, Wu, Binlin, Yu, Xinguang, Zhang, Chunyuan, Zhang, Lin, Zhao, Mingyue, Zhou, Yan, Zhu, Ke, Zong, Rui   +12 more
core   +1 more source

CNS tumor with CREBBP::BCORL1 Fusion and pathogenic mutations in BCOR and CREBBP: expanding the spectrum of BCOR-altered tumors

Acta Neuropathologica Communications
The fifth edition of the World Health Organization (WHO) classification of central nervous system (CNS) tumors introduced the new tumor type CNS tumor with BCOR internal tandem duplication (ITD), characterized by a distinct DNA methylation profile and ...
Valeria Barresi, Antonello Cardoni, Evelina Miele, Lucia Pedace, Barbara Masotto, Claudia Nardini, Sabina Barresi, Sabrina Rossi   +7 more
doaj   +1 more source