Results 61 to 70 of about 28,422 (183)

Homology operations and cosimplicial iterated loop spaces

open access: yes, 2014
If X is a cosimplical $E_{n+1}$ space then Tot(X) is an $E_{n+1}$ space and its mod 2 homology $H_*(Tot(X))$ has Dyer-Lashof and Browder operations. It's natural to ask if the spectral sequence converging to $H_*(Tot(X))$ admits compatible operations. In
Hackney, Philip
core   +1 more source

ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju   +11 more
wiley   +1 more source

Machine Learning Based on Digital Image Colorimetry Driven In Situ, Noncontact Plasma Etch Depth Prediction

open access: yesAdvanced Intelligent Systems, Volume 8, Issue 1, January 2026.
A real‐time and noncontact approach predicts etch depth in plasma etching using digital image colorimetry and machine learning. Red, green, and blue features from in situ images enable accurate predictions without relying on process parameters. Optical emission spectroscopy provides process diagnostics, ensuring stable operating conditions. This method
Minji Kang   +14 more
wiley   +1 more source

Divergent Evolution and Local Establishment of Multidrug‐Resistant Shigella sonnei in China

open access: yesMedComm, Volume 7, Issue 1, January 2026.
• Evolutionary history and local establishment of Chinese Shigella sonnei are unclear. • Chinese S. sonnei developed into four clades and ONPG‐negative variants. • The antimicrobial resistance phenotype of Clade I was due to an IncB/O/K/Z plasmid. • Antimicrobial resistance of Clade II was due to IncFII and IncB/O/K/Z plasmids.
Kangkang Liu   +26 more
wiley   +1 more source

Cuadro de mando para el monitoreo y control de indicadores de gestión en procesos de investigación, innovación y emprendimiento en Nicaragua

open access: yesEl Higo, 2019
Con el propósito de desarrollar un sistema de Información Gerencial de los indicadores de ciencia, tecnología e innovación para el monitoreo y control de los procesos de investigación, innovación y emprendimiento de las universidades miembros del ...
Juan de Dios Bonilla Anduray   +1 more
doaj   +1 more source

A Mechanism‐Based Multi‐Level Population PK/PD Model for Potassium‐Competitive Acid Blockers

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
Schematic overview of a mechanism‐based, multi‐level population model for potassium‐competitive acid blockers. ABSTRACT Potassium‐competitive acid blockers (PCABs) are emerging alternatives to proton pump inhibitors for the treatment of acid‐related diseases.
Woojin Jung   +6 more
wiley   +1 more source

Phase II open‐label multicenter study to assess the antitumor activity of afatinib in lung cancer patients with activating epidermal growth factor receptor mutation from circulating tumor DNA: Liquid‐Lung‐A

open access: yesThoracic Cancer, 2021
Background Mutation analysis of circulating tumor DNA (ctDNA) is used for diagnosing lung cancer. This trial aimed to assess the efficacy of afatinib in treatment‐naïve patients with lung cancer harboring epidermal growth factor receptor mutations (EGFRm,
Cheol‐Kyu Park   +7 more
doaj   +1 more source

Targeted Nanocomplex Delivery for Protecting Vascular Integrity and Enhancing Anticancer Effects in Hepatocellular Carcinoma

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim   +11 more
wiley   +1 more source

Sur et pour… mais pas avec. Recherches doctorales sur le numérique en éducation

open access: yesQuestions Vives, 2020
The author proposes a study of the abstracts of thesis on the digital of the doctors who submitted a dossier of qualification to the functions of lecturer, at the 70th section of the CNU, between 2015 and 2019.
Jean-Luc Rinaudo
doaj   +1 more source

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

open access: yesSmall Methods, Volume 10, Issue 2, 22 January 2026.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah   +8 more
wiley   +1 more source

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