Results 41 to 50 of about 112,737 (278)

Preparing for (valenced) action: the role of differential effort in the orthogonalized go/no-go task [PDF]

open access: yes, 2016
Associating reward to task performance has been shown to benefit scores of cognitive functions. Importantly, this typically entails associating reward to the execution of a response, hence intertwining action-related processes with motivational ones ...
Bombeke, Klaas   +3 more
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

An Attempt to Find Alternative Stains for Routine Hematoxylin and Eosin

open access: yesRGUHS Journal of Medical Sciences
Background Universally accepted stains for the routine histopathological examination are Hematoxylin and Eosin. There are even special stains that would specifically stain the individual tissue architecture such as stains for ...
Ram Kumar Tirandas, Akhila CNV
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Adhesion failures determine the pattern of choroidal neovascularization in the eye: a computer simulation study. [PDF]

open access: yesPLoS Computational Biology, 2012
Choroidal neovascularization (CNV) of the macular area of the retina is the major cause of severe vision loss in adults. In CNV, after choriocapillaries initially penetrate Bruch's membrane (BrM), invading vessels may regress or expand (CNV initiation ...
Abbas Shirinifard   +6 more
doaj   +1 more source

JAX-CNV: A Whole-genome Sequencing-based Algorithm for Copy Number Detection at Clinical Grade Level

open access: yesGenomics, Proteomics & Bioinformatics, 2022
We aimed to develop a whole-genome sequencing (WGS)-based copy number variant (CNV) calling algorithm with the potential of replacing chromosomal microarray assay (CMA) for clinical diagnosis.
Wan-Ping Lee   +10 more
doaj   +1 more source

Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]

open access: yes, 2017
Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria   +5 more
core   +3 more sources

TTT and CNV [PDF]

open access: yesBritish Journal of Ophthalmology, 2001
Editor,—We thank Ergun and Stur1 for their interest in our paper and agree with their comments that it is not possible to directly compare a pilot study with the results of a randomised controlled study. We also pointed out in our conclusion that studies such …
openaire   +3 more sources

Effects of Copy Number Variations on Developmental Aspects of Children With Delayed Development [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2019
Objective To determine effects of copy number variations (CNV) on developmental aspects of children suspected of having delayed development. Methods A retrospective chart review was done for 65 children who underwent array-comparative genomic ...
Kee-Boem Park   +5 more
doaj   +1 more source

Using GWAS Data to Identify Copy Number Variants Contributing to Common Complex Diseases

open access: yes, 2010
Copy number variants (CNVs) account for more polymorphic base pairs in the human genome than do single nucleotide polymorphisms (SNPs). CNVs encompass genes as well as noncoding DNA, making these polymorphisms good candidates for functional variation ...
Teslovich, Tanya M., Zöllner, Sebastian
core   +1 more source

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