Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Clouds are a key player in the global climate system, affecting the atmospheric water and energy budgets, and they are strongly coupled to the large‐scale atmospheric circulation.
Guy Dagan +3 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Co-circulation and co-infection of COVID-19 and influenza in China: challenges and implications
Qingchun Pan +4 more
doaj +1 more source
The Measurement of Co-Circulation of Currencies and Dollarization in the Republic of Armenia [PDF]
This paper attempts to estimate the actual (de facto) level of dollarization in Armenia. "Co-circulation" involves the regular use of two or more currencies within an economy.
Hakob Zoryan
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Co-circulation and co-infection: parasite interactions across scales
Parasite-parasite interactions occur both within and between hosts, but the two scales are rarely considered together. Consequently, there is a gap in our ability to predict the integrated effects of interactions occurring across scales, disentangle their relative contributions to key ecological outcomes, and accurately identify the drivers of host ...
Giacomo Zilio +13 more
openaire +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Temporal Co-circulation Patterns of Respiratory Pathogens in South Africa, 2024: A Retrospective Analysis of Private Laboratory Surveillance Data [PDF]
Background and study aim: Respiratory tract infections cause substantial morbidity, and multiplex polymerase chain reaction (PCR) testing demonstrates concurrent circulation of multiple respiratory pathogens.
Somasundram Pillay
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

