Results 91 to 100 of about 6,704,341 (266)

On Co-Creation

CERN IdeaSquare Journal of Experimental Innovation
It is hard to imagine a better home for an issue on co-creation than this journal. CERN is itself among the great standing demonstrations of co-creation: between nation-states, between disciplines - art and science meeting at the highest levels - in ...
Andrew Dubber, Michela Magas
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Languaging Co-Creation

CERN IdeaSquare Journal of Experimental Innovation
Presented as an alphabetical glossary of concepts and neologisms, this paper depicts human co-creation as a potential global resource for turning existential 'unthinkables' into micro-utopian 'possibles'.
John Wood
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Internet-based consumer co-creation experience of the new product development process

Engineering Management in Production and Services, 2019
The paper aims to explore consumer co-creation experience of new product development processes. Specifically, it is an attempt to determine the level of consumer engagement in an online co-creation process, identifying motives and reasons for the ...
Khrystoforova Viktoria, Siemeniako Dariusz   +1 more
doaj   +1 more source

Automatic Identification of Critical Damage Value with In-situ Shearing Test and Notched Plate Tensile Test with Image Analysis [PDF]

MATEC Web of Conferences
Critical damage values in Cockcroft and Latham's and Ayada's models are automatically identified using autonomous-driven finite element analysis (ADFEA). To validate fracture behavior, we perform in-situ shearing and tensile tests on notched steel plates,
Yoshida Yoshinori, Kutsukake Asuka
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Role of Empathetic Company Philosophy and Advanced Technologies in Shaping Job Attitudes

Business Systems Research
Although the literature has assessed various factors underlying employee attitudes, knowledge of company philosophy and advanced technology is lacking, especially in the context of the major drivers of job satisfaction and turnover intentions.
Koizumi Masaki, Kato Takumi
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source