Results 221 to 230 of about 408,394 (320)

Rethinking Co-Creation

This paper reflects on the pilot study of the Vietnam Design Research Studio in Hoa Tien, a traditional craft village, which sought to explore co-creation methodologies in the context of digital platform development. Initial ambitions to collaboratively design a digital tool with local artisans confronted significant challenges, revealing inherent ...
Donna, Cleveland, Corinna, Joyce, Peter, Cleveland, Matthias, Waldhart, Anna, Rylander, Hanh, Nguyen   +5 more
openaire   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Fueling Inner Resources Through Co-Creation: A Scoping Review on the Impact of Co-Creation of Education on Learners' Well-Being. [PDF]

Perspect Med Educ
Suliman S, Iqbal MZ, Bishawi AH, Allen M, Könings KD.   +4 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Co-Creation and Validation of a Social Media Resource for Mental Health Literacy Among Spanish Adolescents. [PDF]

Health Expect
Casañas R, Hernández Encuentra E, Martín J, Lalueza F, Boixadós M.   +4 more
europepmc   +1 more source

A Reflective Shift towards Student–Staff Partnerships for Inclusive and Decolonial Curriculum Co-Creation in the Global South [PDF]

openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Illustrating Key Components to Co-Creation Through Preventive Care mHealth Messaging with Underserved Communities and Expert Partners. [PDF]

J Med Syst
Stadnick NA, Geremia C, Cain KL, Oswald W, Watson P, Ibarra M, Nguyen M, Altemimi Z, Hammi N, Bautista M, Alrefaee M, Chu TM, Wagner NM, Vijaykumar S, O'Leary ST, Diaz EA, Aldous J, Rabin BA.   +17 more
europepmc   +1 more source

Detection of Territorial Challenges and Co-creation of Knowledge [PDF]

Òscar Redondo
openalex   +1 more source