Co-design - Open Access .click

Results 81 to 90 of about 1,996,608 (264)

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source

Co-design of a Smart Cajón

Journal of the Audio Engineering Society, 2018
The work of Luca Turchet is supported by a Marie-Curie Individual fellowship of European Union’s Horizon 2020 research and innovation program, under grant agreement No. 749561. Mathieu Barthet also acknowledges support from the EU H2020 Audio Commons grant (688382).
Turchet L, McPherson A, Barthet M
openaire +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source

A Mathematical Theory of Co-Design

CoRR, 2015
One of the challenges of modern engineering, and robotics in particular, is designing complex systems, composed of many subsystems, rigorously and with optimality guarantees. This paper introduces a theory of co-design that describes "design problems", defined as tuples of "functionality space", "implementation space", and "resources space", together ...
openaire +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

Research on the collaborative mechanism between site selection optimization model and control of green space planning under the background of urban renewal

Discover Sustainability
As a part of integrated urban ecosystems, green space is an important target of urban renewal planning. In the process of urban renewal of green space, it is difficult to control the special planning for green space systems, and the scale of urban public
Xiangyun Li, Desheng Dai, Jingwen Dong, Kaili Hu +3 more
doaj +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

Spanning capacity analysis of self-anchored suspension bridges based on the stability and compression strength of stiffening girder

Journal of Asian Architecture and Building Engineering
Considerable axial compression stress exists in the stiffening girder of self-anchored suspension bridges. Therefore, failures of self-anchored suspension bridges will be either due to material failure or instability of the stiffening girder, which will ...
Cunyu Cui +3 more
doaj +1 more source

Research on integrated sensing and communication technology towards 5G evolution

Dianzi Jishu Yingyong
Integrated Sensing and Communication (ISAC),as a core technology for 5.5G/6G systems,breaks the functional boundaries of traditional systems by deeply integrating communication and sensing capabilities,enabling shared spectrum and hardware resources,and ...
Bai Bo, Liu Shun, Dong Peng, Hu Jian
doaj +1 more source

environmental sciences
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