Results 61 to 70 of about 1,061,676 (247)

Caribou Co-Management Needs From Research: Simple questions - Tricky answers

open access: yesRangifer, 1996
Over the past decade, northern Canada has experienced a substantial increase in government reliance on advisory co-management organizations to manage caribou populations.
Doug Urquhart
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Settlements of the future [PDF]

open access: yesUrbani Izziv, 2002
Current ongoing societal processes allow me to say that all humanity must foresee the great opportunity to change direction from market driven development to human scale sustainable development as the only way to achieve whole scale growth.
Domen Zupančič
doaj  

Cockles in custody: the role of common property arrangements in the ecological sustainability of mangrove Fisheries on the Ecuadorian Coast

open access: yesInternational Journal of the Commons, 2011
Scholars of common property resource theory (CPR) have long asserted that certain kinds of institutional arrangements based on collective action result in successful environmental stewardship, but feedback and the direct link between social and ...
Christine M. Beitl
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Chronicle of a Demise Foretold: State vs. Local Groundwater Management in Texas and the High Plains Aquifer System

open access: yesWater Alternatives, 2018
This paper assesses a case of co-management of groundwater between the state of Texas, pushing for the rationalisation of groundwater management, and local (mainly farming) communities organised in Groundwater Conservation Districts (GCDs), which are ...
Alvar Closas , François Molle
doaj  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Gestão integrada e participativa em ambientes costeiros: estudo de caso do Projeto Orla no município de Balneário Rincão, SC, Brasil

open access: yesDesenvolvimento e Meio Ambiente, 2016
The Brazilian coastal zone is singular by its historical socioeconomic importance and natural richness, where highly polluting activities coexists with valuable environmental resources.
Carlyle Torres Bezerra de Menezes   +3 more
doaj   +1 more source

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