Results 101 to 110 of about 3,096,144 (304)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Global trends in ICT-based extension and advisory services in agriculture: a bibliometric analysis

Frontiers in Sustainable Food Systems
Utilizing Information and Communication Technology (ICT) to grant farmers direct access to information, while also developing models tailored to the specific contexts of both public and private agricultural extension sectors, stands as a pivotal endeavor
Sweety Mukherjee, Rabindra Nath Padaria, Rajarshi Roy Burman, Praveen Koovalamkadu Velayudhan, Girijesh Singh Mahra, Kaustav Aditya, Subhashree Sahu, Sushmita Saini, Sonali Mallick, Sk. Wasaful Quader, K. Shravani, Bhaskar Ghosh, Adarsha Gopalakrishna Bhat   +12 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

ANALISIS TEKSTUR PADA CITRA IRIS MATA MENGGUNAKAN ALGORITMA GRAY LEVEL CO-OCCURENCY MATRIX

Pilar Nusa Mandiri, 2019
According to data from the ministry of health, with the high intensity of use the gadget nowadays, therefore the number of people with eye disease is increasing.
Asti Herliana, Toni Arifin
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Navigating the green finance frontier: a bibliometric and content analysis of green finance and environmental sustainability

Cogent Economics & Finance
The present study explores the intersection between green finance (GF) and environmental sustainability (ES) with the help of comprehensive bibliometric and content analysis techniques, unveiling new perspectives on this synergy and contributing novel ...
Ashish Kumar, Suman Ahuja, Nupur Soti, A.K Saini, Bharti   +4 more
doaj   +1 more source

Jaccard/Tanimoto similarity test and estimation methods

, 2019
Binary data are used in a broad area of biological sciences. Using binary presence-absence data, we can evaluate species co-occurrences that help elucidate relationships among organisms and environments.
Chung, Neo Christopher, Gambin, Anna, Miasojedow, Błażej, Startek, Michał   +3 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Formation of a tourist destination image: Co-occurrence analysis of destination promotion videos

Journal of Destination Marketing & Management, 2023
B. Zuo, C. Tsai, C. Su, Nitchamon Jantes, Ming-Hsiang Chen, Jiaxue Liu   +5 more
semanticscholar   +1 more source