Results 81 to 90 of about 27,417,864 (309)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Bibliometric Analysis of Strategic Agility Using Word Co-occurrence Analysis [PDF]

‫مدیریت بازرگانی
Objective Strategic agility, as one of the key concepts in strategic management, has attracted the attention of many researchers and managers. However, the concept remains controversial and is considered non-intuitive and intangible by some scholars ...
Ata Harandi, Alireza Mohebbi
doaj   +1 more source

Co-occurrence of adult abuse and child abuse: analysis of the phenomenon.

Journal of injury & violence research, 2022
The purpose of this study was to analyze the co-occurrence of adult and child abuse based on the reports collected from the Polish police and social welfare institutions.The study involved data concerning 468 households in Szczecin (Poland) inhabited by children where acts of violence between adults took place.
Kożybska, Marta, Giezek, Marta, Zabielska, Paulina, Masna, Barbara, Ciechowicz, Jacek, Paszkiewicz, Monika, Kotwas, Artur, Karakiewicz, Beata   +7 more
openaire   +2 more sources

Phylogenetic and adaptive components of the anuran advertisement call correlate with temporal species co-occurrence

, 2018
Vocalization is the major means of communication in animal groups and crucial in mate recognition. The call is composed by spectral parameters (i.e., physical structure of the call) and temporal (i.e., time-quantized parameters), whose evolution can be ...
Denise de Cerqueira Rossa-Feres (3243816), Thiago Gonçalves-Souza (5614645), Michel V. Garey (3133455), Célio F. B. Haddad (5614650), Diogo Provete (444095), Lilian Sayuri Ouchi-Melo (5614647)   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Green banking disclosure: A bibliometric analysis

Ho Chi Minh City Open University Journal of Science - Economics and Business Administration
This study uses a bibliometric approach to analyze the influence and productivity of research on green banking disclosure from 1993 to 2023. We utilize the Web of Science Core Collection database to gather the 112 articles, and Biblioshiny software to ...
Sa Nguyen Tran, Dao Thi Thieu Ha
doaj   +1 more source

Relationship between artificial intelligence and legal education: A bibliometric analysis [PDF]

Knowledge & Performance Management
This study aims to explore past research trends and identify key future directions at the intersection of artificial intelligence and legal education. The study’s data were gathered from the Scopus database, comprising 68 selected documents spanning from
Diep Dao Mong, Hai Phan Thanh
doaj   +1 more source

Analysis of category co-occurrence in Wikipedia networks

, 2019
Wikipedia has seen a huge expansion of content since its inception. Pages within this online encyclopedia are organised by assigning them to one or more categories, where Wikipedia maintains a manually constructed taxonomy graph that encodes the semantic relationship between these categories. An alternative, called the category co-occurrence graph, can
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source