Results 61 to 70 of about 27,417,864 (309)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Some Comments on the Question Whether Co-occurrence Data Should Be Normalized [PDF]

open access: yes
In a recent paper in the Journal of the American Society for Information Science and Technology, Leydesdorff and Vaughan assert that raw cocitation data should be analyzed directly, without first applying a normalization like the Pearson correlation.
Waltman, L.R., Eck, N.J.P. van
core   +2 more sources

TRENDS AND GLOBAL COLLABORATION IN SUSTAINABLE DEVELOPMENT GOALS ACCOUNTING [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
The integration of Sustainable Development Goals (SDGs) into accounting practices has gained significant academic and professional attention as organizations seek to align their financial and non-financial reporting with global sustainability ...
CÎRSTEA ANDREEA
doaj  

Co-occurrence matrix for the total dataset.

open access: yes, 2022
Co-occurrence matrix for species showing significant associations in the whole dataset. Positive associations are blue; negative associations are yellow. (EPS)
Emily G. Mitchell (8706969)   +2 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Marketing concept evolution: a bibliometrics co-occurrence analysis

open access: yesMarketing and Management of Innovations, 2019
У статті розглянуто еволюцію розвитку концепції маркетингу початку нового тисячоліття. Авторами проаналізовано реакцію науковців, що досліджують питання маркетингу, на реформи 2006 року у Туреччині. Головною метою статті є визначення напрямів розвитку маркетингової концепції до впровадження реформ, аналіз впливу впровадження реформ на зміну ...
Taqi, M., Gurkaynak, N., Gencer, M.
openaire   +2 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Cloud Computing and Energy Efficiency: Mapping the Thematic Structure of Research

open access: yesEnergies, 2020
The dynamic growth in the use of cloud computing systems results in increasing energy consumption. Consequently, more and more attention is given to energy efficiency issues both in research and theory development as well as the business practice of ...
Andrzej Lis   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Effects of Different Heavy Metal Stressors on the Endophytic Community Composition and Diversity of Symphytum officinale

open access: yesMicroorganisms
Endophytes play an important role in helping plants resist heavy metal stress. However, little is known about the effects of different heavy metals on the diversity and composition of endophyte communities.
Jing Ma   +8 more
doaj   +1 more source

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