Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Trends and Future Research in Electronic Marketing: A Bibliometric Analysis of Twenty Years
Journal of Theoretical and Applied Electronic Commerce Research, 2021 Electronic marketing (eM) is a flourishing phenomenon that is gaining intense concern because of a significant impact on organizational performance. Over the past few decades, the relevance of eM has been observed in numerous fields (e.g., consumers ...
Peng Gao +9 more
doaj +1 more source
On the puzzling feature of the silence of precursory electromagnetic emissions [PDF]
, 2013 It has been suggested that fracture-induced MHz-kHz electromagnetic (EM) emissions, which emerge from a few days up to a few hours before the main seismic shock occurrence permit a real-time monitoring of the damage process during the last stages of ...
Chelidze, T. +2 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fire disturbance disrupts co-occurrence patterns of terrestrial vertebrates in Mediterranean woodlands [PDF]
, 2006 This paper uses null model analysis to explore the pattern of species co-occurrence of terrestrial vertebrate fauna in fire-prone, mixed evergreen oak woodlands.
BELLIA, Enrico +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Proposed Algorithm For Using GLCM Properties To Distinguishing Geometric Shapes [PDF]
Al-Rafidain Journal of Computer Sciences and Mathematics, 2019 In this research, an algorithm was used to look at the characteristics of a set of images for geometric shapes and then to classify them into totals based on four characteristics obtained from the co-occurrence matrix (energy, contrast, correlation and ...
Kifaa Thanoon
doaj +1 more source
A single case study of a family-centred intervention with a young girl with cerebral palsy who is a multimodal communicator [PDF]
, 2011 Background - This paper describes the impact of a family-centred intervention that used video to enhance communication in a young girl with cerebral palsy.
Bailey +25 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Evaluation of Statistical Features for Medical Image Retrieval [PDF]
, 2013 In this paper we present a complete system allowing the classification of medical images in order to detect possible diseases present in them. The proposed method is developed in two distinct stages: calculation of descriptors and their classification ...
Di Ruberto C, Fodde G
core +1 more source