Results 71 to 80 of about 17,311 (265)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Some Simple Economics of Energy Transition

Substantia, 2019
After explaining the current climate emergency, this survey article summarises financial cost estimates for transition to zero carbon by 2050, which even in the medium term, neglecting catastrophic climate collapse, are much less than the cost of ...
Felix FitzRoy
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Satellite-Based Assessment of Spatially Heterogeneous XCO₂ and Marine pCO₂ Trends (2015–2020)

Remote Sensing
Satellite remote sensing has revolutionized the monitoring of atmospheric carbon dioxide (CO2) concentrations, yet its integration into studies of air–sea CO2 flux dynamics remains limited. Leveraging high-resolution observations from the Orbiting Carbon
Siqi Zhang, Zhenhua Zhang, Peng Chen, Haiqing Huang, Delu Pan   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Regulating Thermal Performance and Emission Characteristics of a Large-Bore Two-Stroke Marine Diesel Engine Fueled with Methyl Decanoate/Diethyl Ether Blends: A Full-Cylinder CFD Study

Journal of Marine Science and Engineering
A full-cylinder CFD model was developed to investigate methyl decanoate (MD)/diethyl ether (DEE) blends in a MAN B&W 7S80ME-C9 two-stroke diesel engine at 75% load.
Shiye Wang, Peiyuan Wang, Jianghua Sui, Haopeng Chen   +3 more
doaj   +1 more source

The Virtual Teacher (VT) Paradigm: Learning New Patterns of Interpersonal Coordination Using the Human Dynamic Clamp.

PLoS ONE, 2015
The Virtual Teacher paradigm, a version of the Human Dynamic Clamp (HDC), is introduced into studies of learning patterns of inter-personal coordination.
Viviane Kostrubiec, Guillaume Dumas, Pier-Giorgio Zanone, J A Scott Kelso   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Assessing effectiveness of serious game training designed to assist in upper limb prosthesis rehabilitation

Frontiers in Rehabilitation Sciences
IntroductionControlling a myoelectric upper limb prosthesis is difficult, therefore training is required. Since training with serious games showed promising results, the current paper focuses on game design and its effectivity for transfer between in ...
Bart Maas, Corry K. Van Der Sluis, Raoul M. Bongers   +2 more
doaj   +1 more source