Results 81 to 90 of about 1,054,030 (246)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research on the process of naphtha hydrocracking to chemical materials

open access: yesCarbon Resources Conversion
To systematically study the conversion process of paraffin, cycloalkane, and aromatic on ZSM-5 molecular sieve in naphtha hydrocracking, a series of related experiments were carried out based on the prepared hydrocracking catalyst, Catalyst-HC.
Kui Zhang   +6 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Influence of austenitizing parameters on microstructure and mechanical properties of Al-Si coated press hardened steel

open access: yesMaterials & Design, 2019
The influence of the austenitizing parameters on the microstructure and mechanical behavior of Al-Si coated press hardened 22MnB5 steel was evaluated in this study.
Lindsay Golem   +3 more
doaj   +1 more source

Assessing dynamic brain activity during verbal associative learning using MEG/fMRI co-processing. [PDF]

open access: yesNeuroimage Rep, 2023
Nair S   +5 more
europepmc   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Accelerated Ferrite-to-Austenite Transformation During Intercritical Annealing of Medium-Manganese Steels Due to Cold-Rolling

open access: yesMetals, 2019
Prior cold deformation is known to influence the ferrite-to-austenite (α → γ) transformation in medium-manganese (Mn) steels that occurs during intercritical annealing.
Josh J. Mueller   +3 more
doaj   +1 more source

Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi. [PDF]

open access: yesCell Rep Methods, 2022
Amen AM   +9 more
europepmc   +1 more source

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