Results 101 to 110 of about 1,748,214 (284)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A Combined Immersed Boundary Method for Flows with Scalar Transport

Journal of Chemical Engineering of Japan
A solid volume fraction type immersed boundary method and a ghost cell immersed boundary method are combined for solving flows with scalar transport such as concentration of chemical species and heat.
Yuta Yaegashi, Hiroki Muramatsu, Naoki Shimada, Yusuke Uchihashi, Mako Sato   +4 more
doaj   +1 more source

Triple helix networks matching knowledge demand and supply in seven Dutch horticulture Greenport regions [PDF]

, 2017
This paper investigates the triple helix (industry, knowledge workers and governments) cooperation on knowledge co-production and valorisation for innovation, which took place in seven horticultural regions in the Netherlands.
Dijkshoorn-Dekker, Marijke W.C., Geerling-Eiff, Florentien A., Hoes, Anne-Charlotte   +2 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Research on key technology of packer rubber barrel for integrated fracturing and completion of gas well

Journal of Petroleum Exploration and Production Technology
The staged and layered fracturing technology plays an important role in unconventional tight reservoirs. And the gas well fracturing and completion integration is the core component to realize the fracturing and completion integration process, which can ...
Peng Wang, Meng Cai, Zhaoyi Liu, Wenhai Ma, Junliang Li   +4 more
doaj   +1 more source

Hydrophobized Reversed-Phase Adsorbent for Protection of Dairy Cattle against Lipophilic Toxins from Diet. Efficiensy In Vitro and In Vivo

Toxins, 2019
The steady growth of inflammatory diseases of the udder in dairy cattle forces us to look for the causes of this phenomenon in the context of growing chemical pollution of the environment and feeds.
Alexander Sotnichenko, Evgeny Pantsov, Dmitry Shinkarev, Victor Okhanov   +3 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Co-production : a defence of young people [PDF]

, 2018
Recent years have seen fundamental and challenging changes in the delivery of services for young people. Outcomes, outputs and interventions have become the language of service evaluations, and allocation of funding creating an instrumental environment ...
Gornall, Lesley
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Mechanism of Water Film Acting on Capillary Force in Porous Media of Tight Reservoirs

Liaoning Shiyou Huagong Daxue xuebao
The water film formed within the pores of tight reservoirs leads to a distinct "oil⁃core water⁃film" configuration in the distribution of oil and water within the porous medium, which has a significant impact on the flow channels and capillary forces of ...
Xiaoxu DAI, Xiaowei FENG, Zeng WANG, Lihua SHI, Pingping HUO   +4 more
doaj   +1 more source