Results 41 to 50 of about 280,105 (248)

PID-Based Longitudinal Control of Platooning Trucks

Machines, 2023
This article focuses on the development and assessment of a PID-based computationally cost-efficient longitudinal control algorithm for platooning trucks.
Aashish Shaju, Steve Southward, Mehdi Ahmadian   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A bootstrapping method to optimize go/no‐go decisions from single‐arm, signal‐finding studies in oncology

CPT: Pharmacometrics & Systems Pharmacology
Phase Ib trials are common in oncology development but often are not powered for statistical significance. Go/no‐go decisions are largely driven by observed trends in response data.
Raunak Dutta, Aparna Mohan, Jacqueline Buros‐Novik, Gregory Goldmacher, Omobolaji O. Akala, Brian Topp   +5 more
doaj   +1 more source

Co-Simulation and Modeling of PMSM Based on Ansys Software and Simulink for EVs

World Electric Vehicle Journal, 2021
Electric vehicles (EVs) should have an electrical motor with high efficiency, high power density, and a wider constant power operating region, as well as ease of control and inexpensive manufacturing cost.
Tewodros Kassa Mersha, Changqing Du
doaj   +1 more source

Checking SysML Models for Co-simulation

, 2016
Cyber-physical systems (CPSs) are often treated modularly to tackle both complexity and heterogeneity; and their validation may be done modularly by co-simulation: the coupling of the individual subsystem simulations. This modular approach underlies the FMI standard.
Amalio, Nuno, Payne, Richard, Cavalcanti, Ana, Woodcock, Jim   +3 more
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Scalable Joint Estimation Algorithm for SOC and SOH of All Individual Cells within the Battery Pack and Its HIL Implementation

World Electric Vehicle Journal
Accurately obtaining the state of charge (SOC) and health (SOH) of all individual batteries in a battery pack can provide support for data acquisition, state estimation, and fault diagnosis.
Yongshan Liu, Di Zhang, Fan Wang, Tengfei Huang, Yuanbin Yu, Fangjie Sun   +5 more
doaj   +1 more source

MOSAIK and FMI-Based Co-Simulation Applied to Transient Stability Analysis of Grid-Forming Converter Modulated Wind Power Plants

Applied Sciences, 2021
The grid integration of renewable energy sources interfaced through power electronic converters is undergoing a significant acceleration to meet environmental and political targets.
Nakisa Farrokhseresht, Arjen A. van der Meer, José Rueda Torres, Mart A. M. M. van der Meijden   +3 more
doaj   +1 more source

Co-simulation: State of the art

, 2017
It is essential to find new ways of enabling experts in different disciplines to collaborate more efficient in the development of ever more complex systems, under increasing market pressures. One possible solution for this challenge is to use a heterogeneous model-based approach where different teams can produce their conventional models and carry out ...
Gonçalves Gomes, Claudio Angelo, Thule, Casper, Broman, David, Larsen, Peter Gorm, Vangheluwe, Hans   +4 more
openaire   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source