Results 51 to 60 of about 7,877,554 (342)

Error Analysis and Error Estimates for Co-simulation in FMI for Model Exchange and Co-Simulation v2.0 [PDF]

Archive of Mechanical Engineering, 2013
Complex multi-disciplinary models in system dynamics are typically composed of subsystems. This modular structure of the model reflects the modular structure of complex engineering systems. In industrial applications, the individual subsystems are often modelled separately in different mono-disciplinary simulation tools.
Martin Arnold, Christoph Clauss, Tom Schierz   +2 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Co-simulation of Matlab/Simulink with AMS designer in system-on-chip design

, 2022
S.57-63With increasing complexity of Systems-on-Chips (SoC), system level design and simulation is a necessity. In an ideal top-down design flow, the system level model is used as executable specification for the block implementation, which is supported ...
Knöchel, U., Eichler, Uwe, Hartong, W., Hartung, J., Altmann, S.   +4 more
core   +1 more source

Research on Performance of Real-Time Simulation Based on Inverter-Dominated Power Grid

IEEE Access, 2021
This paper proposes two methods to improve the performance in real-time simulation. The increased inverter-based generations are gradually shifting the operation of the power grid.
Xinya Song, Hui Cai, Teng Jiang, Tom Sennewald, Jan Kircheis, Steffen Schlegel, Leonel Noris Martinez, Youcef Benzetta, Dirk Westermann   +8 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A bootstrapping method to optimize go/no‐go decisions from single‐arm, signal‐finding studies in oncology

CPT: Pharmacometrics & Systems Pharmacology
Phase Ib trials are common in oncology development but often are not powered for statistical significance. Go/no‐go decisions are largely driven by observed trends in response data.
Raunak Dutta, Aparna Mohan, Jacqueline Buros‐Novik, Gregory Goldmacher, Omobolaji O. Akala, Brian Topp   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A Scalable Joint Estimation Algorithm for SOC and SOH of All Individual Cells within the Battery Pack and Its HIL Implementation

World Electric Vehicle Journal
Accurately obtaining the state of charge (SOC) and health (SOH) of all individual batteries in a battery pack can provide support for data acquisition, state estimation, and fault diagnosis.
Yongshan Liu, Di Zhang, Fan Wang, Tengfei Huang, Yuanbin Yu, Fangjie Sun   +5 more
doaj   +1 more source

Behavioural Models for FMI Co-simulations [PDF]

, 2016
Simulation is a favoured technique for analysis of cyber-physical systems. With their increase in complexity, co-simulation, which involves the coordinated use of heterogeneous models and tools, has become widespread. An industry standard, FMI, has been developed to support orchestration; we provide the first behavioural semantics of FMI.
Cavalcanti, A. L. C., Woodcock, J. C. P., Amalio, N.   +2 more
openaire   +3 more sources