Results 71 to 80 of about 7,877,554 (342)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Modeling and Subjective Evaluation Method of Driveability for Fuel Cell Vehicles

Energies
Aiming at the demand for subjective evaluation of driveability for fuel cell vehicles, the modeling and evaluation method of driveability for fuel cell vehicles were studied in this paper.
Jun Zhan, Huainan Zhu, Chunguang Duan, Zhao-Hui Zhong, Wei Huang, Baoli Zhu, Guangjian Xu   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

TLM-Based Asynchronous Co-simulation with the Functional Mockup Interface

, 2019
Numerical stability is a key aspect in co-simulation of physical systems. Decoupling a system into independent sub-models will introduce time delays on interface variables.
Hällqvist, Robert,, Fritzson, Dag,, Braun, Robert,   +2 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The Pacific co-operator.

, 1913
Published by, : Pacific Co-operative League.Published by, Aug. 1913- : Co-operative Publishing Company.Official organ for the Farmers' Co-operative Educational Union of America, California Division, and the Rochdale Co-operative Societies of California ...
Rochdale Co-operative Societies of California., Pacific Co-operative League.   +1 more
core  

Functional Mockup Interface 2.0: The Standard for Tool independent Exchange of Simulation Models [PDF]

, 2012
The Functional Mockup Interface (FMI) is a tool independent standard for the exchange of dynamic models and for Co-Simulation. The first version, FMI 1.0, was published in 2010. Already more then 30 tools support FMI 1.0.
Neumerkel, Dietmar, Markus Friedrich, Viel, A., Johan Akesson, Hans Olsson, Friedrich, M., Andreas Junghanns, Akesson, J., Junghanns, Andreas, Arnold, Martin, Hilding Elmqvist, Torsten Blockwitz, Olsson, Hans, Jakob Mauss, Åkesson, Johan, Antoine Viel, Otter, Martin, Clauß, C., Friedrich, Markus, Viel, Antoine, Mauss, Jakob, Christoph Clauss, Blockwitz, T., Dietmar Neumerkel, Blochwitz, Torsten, Elmqvist, Hilding, Martin Otter, Neumerkel, D., Martin Arnold, Junghanns, A., Åkesson, Johan,, Lund University., Mauss, J., Olsson, H., Clauss, Christoph   +34 more
core   +1 more source

Business success through process based application of simulation [PDF]

, 2008
Progressive design practices are increasingly cognisant of the potential of building energy simulation to assist the delivery of energy efficient, sustainable buildings.
Cockroft, Jeremy, McElroy, L.B., Hand, Jon, McElroy, Lori, Hand, J., Cockroft, J.   +5 more
core   +4 more sources

Numerical study of thermal-hydraulic behavior on the integral test facility of HPR1000 containment based on CONTHAC-3D

Nuclear Engineering and Technology
The integral test facility-platform for the integral thermal-hydraulic behavior of containment (PANGU), is used to study the thermal-hydraulic behavior of the containment under the action of the passive containment heat removal system (PCS) when accident
Ji Xing, Yuan Chang, Hui Wang, Gong-Lin Li, Ming Ding   +4 more
doaj   +1 more source