Results 81 to 90 of about 7,877,554 (342)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The Development of Social Simulation as Reflected in the First Ten Years of JASSS: a Citation and Co-Citation Analysis [PDF]

Social simulation is often described as a multidisciplinary and fast-moving field. This can make it difficult to obtain an overview of the field both for contributing researchers and for outsiders who are interested in social simulation.
Iris Lorscheid, Klaus G. Troitzsch, Matthias Meyer   +2 more
core  

HintCO – Hint-based Configuration of Co-simulations

Proceedings of the 9th International Conference on Simulation and Modeling Methodologies, Technologies and Applications, 2019
Simulation-based analyses of Cyber-Physical Systems are fundamental in industrial design and testing approaches. The utility of analyses relies on the correct configuration of the simulation tools, which can behighly complicated. System engineers can normally judge the results, and either evaluate multiple simulationalgorithms, or change the models ...
Cláudio Gomes 0001, Bentley James Oakes, Mehrdad Moradi, Alejandro Torres Gámiz, Juan Carlos Mendo, Stefan Dutré, Joachim Denil, Hans Vangheluwe   +7 more
openaire   +4 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

An Improved Collaborative Estimation Method for Determining The SOC and SOH of Lithium-Ion Power Batteries for Electric Vehicles

Energies
With the increase in the amount of actual operating data on electric vehicles, how to analyze and process useful information from existing battery charging and discharging data and apply it to subsequent state estimation is worthy of in-depth thinking ...
Yixin Liu, Ao Lei, Chunyang Yu, Tengfei Huang, Yuanbin Yu   +4 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

State Estimation of Drive-by-Wire Chassis Vehicle Based on Dual Unscented Particle Filter Algorithm

Chinese Journal of Mechanical Engineering
Accurate vehicle dynamic information plays an important role in vehicle driving safety. However, due to the characteristics of high mobility and multiple controllable degrees of freedom of drive-by-wire chassis vehicles, the current mature application of
Zixu Wang, Chaoning Chen, Quan Jiang, Hongyu Zheng, Chuyo Kaku   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source