Results 91 to 100 of about 3,127,636 (279)

Vesicularity, bubble formation and noble gas fractionation during MORB degassing

, 2013
The objective of this study is to use molecular dynamics simulation (MD) to evaluate the vesicularity and noble gas fractionation, and to shed light on bubble formation during MORB degassing.
Aubry, G., Guillot, B., Sator, N.
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

CO2-CH4, and N2O Emissions From Oil Palm Plantation On Deep Peat as Affected by N Fertilization [PDF]

, 2012
Through drainage and nitrogen (N) fertilization, oil palm plantation on peatlands affect emission of the main greenhouse gases (GHG) - carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O).
Bonneau, Xavier, Hergoualc'h, Kristell, Indrasuara, Kooseni, P Handayani, Etik, Van Noordwijk, Meine, Verchot, Louis   +5 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Studie tepelného oběhu s nadkritickým CO2 [PDF]

, 2018
With the increasing interest in solar and geothermal power plants as well as waste heat recovery systems from many technologies, the whole world is more focused on the gas power cycles. Especially, the supercritical carbon dioxide (S-CO2) cycles are very
Veselý Ladislav
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Committed emissions from existing energy infrastructure jeopardize 1.5 °C climate target. [PDF]

, 2019
Net anthropogenic emissions of carbon dioxide (CO2) must approach zero by mid-century (2050) in order to stabilize the global mean temperature at the level targeted by international efforts1-5.
Caldeira, Ken, Davis, Steven J, Hong, Chaopeng, Qin, Yue, Shearer, Christine, Tong, Dan, Zhang, Qiang, Zheng, Yixuan   +7 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Analysis of CO₂ leakage through "low-permeability" faults from natural reservoirs in the Colorado Plateau, southern Utah [PDF]

, 2004
The numerous CO2 reservoirs in the Colorado Plateau region of the United States are natural analogues for potential geologic CO2 sequestration repositories.
Evans, J.P., Heath, J., Kirchner, D., Kolesar, P.T., Shipton, Z.K., Williams, A.P.   +5 more
core  

To develop a new mineral carbonation process that have a high efficiency in CO2 absorption into industry slag using low energy mechanical milling [PDF]

, 2020
Increase in the CO2 emission in atmosphere due to the combustion of fossil fuels has caused serious global warming. Electricity generation, tranportation, and industrial waste are the main sectors indentified to contribute to the emission of CO2 in ...
Selamat, Siti Norhana
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