Results 71 to 80 of about 1,961,078 (257)

Facile and controllable synthesis of BaCO3 crystals superstructures using a CO2-storage material

open access: yesGreen Energy & Environment, 2017
We here report a new CO2 capture and storage method that converts CO2 into a novel alkyl carbonate salt, denoted as CO2SM, by a system consisting of equimolar 1,4-butanediol (BDO) and 1,2-ethylenediamine (EDA).
Feng Sha   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Captura de CO2: tecnologías para una captación a gran escala [PDF]

open access: yes, 2014
Con la publicación de este cuarto volumen nuestra plataforma completa la serie de monografías elaboradas por sus expertos sobre las tecnologías de captura, transporte, almacenamiento y usos del CO2 (tecnologías CAC). La captura, primera de las fases y
Gutiérrez Bravo, José Antonio   +20 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Longyearbyen CO2 Lab - Thermal conductivity

open access: yes
<p>Thermal conductivity data retrieved from the Longyearbyen CO2 Lab boreholes.</p ...
UNIS CO2 Laboratory
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Summary Report of the GCI May 2025 CCU LCA TEA Workshop

open access: yes
This report summarizes the Global CO2 Initiative (GCI) Workshop, which explored key challenges in assessing Carbon Capture, Utilization, and Storage (CCUS) technologies. Three breakout sessions addressed the following topics: 1.
Global CO2 Initiative
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

A global coupled Eulerian-Lagrangian model and 1 × 1 km CO2 surface flux dataset for high-resolution atmospheric CO2 transport simulations [PDF]

open access: yes, 2012
We designed a method to simulate atmospheric CO2 concentrations at several continuous observation sites around the globe using surface fluxes at a very high spatial resolution.
Lukyanov, A   +57 more
core   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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