Results 51 to 60 of about 1,961,078 (257)

Numerical Simulation of Water‐Rock Reaction for CO2 Sequestration in Sandstone Reservoir

Engineering Reports
Climate change represents one of the most pressing global challenges facing humanity. Under the framework of the national climate change strategy, Carbon Capture, Utilization, and Storage (CCUS) is currently regarded as the only viable technology capable
Zhang Yunhai, Wang Shaoqing, Li Qing, Li Jinlong, Song Yan, Chen Xingyu, Yang Bo   +6 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Captura de CO2: tecnologías para cumplir el Acuerdo de París

, 2021
Actualización del monográfico sobre captura del CO2 publicado por PTECO2 en 2014. Una vez superada la crisis financiera y con el horizonte de cumplir el Acuerdo de París, existen novedades suficientes que justifican dicha reedición: En una etapa donde
Serra Alfaro, José Manuel, Mendiara, Teresa, Arias Rozada, Borja, Pevida García, Covadonga, García Labiano, Francisco, Rubiera González, Fernando, Abanades García, Juan Carlos   +6 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

High‐Efficiency CO2 Electrolysis Enabled by Interface‐Engineered Composite Electrolytes in Ni‐Based SOEC

Advanced Science
Interfacial instability between different electrolyte materials is a critical challenge hindering the commercialization of CO2 electrolysis via solid oxide electrolysis cells (SOECs).
Rustam Yuldashev, Hyunchul Jung, Ji Hoon Park, Jin Hee Lee, Min‐Chul Kim   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

CO2 geological storage in sedimentary basins: An update on the potential and suitability evaluation and a field test

Energy Geoscience
China has pledged to peak carbon dioxide (CO2) emissions by 2030 and achieve carbon neutrality by 2060. Carbon capture and storage (CCS) will play a key role in these efforts.
Yujie Diao, Xin Ma, Chenglong Zhang, Xiaolin Jin, Xufeng Li, Chao Zhang   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Synthesis and Thermal Degradation Studies of Melamine Formaldehyde Resins

The Scientific World Journal, 2014
Melamine formaldehyde (MF) resins have been synthesized at different reaction temperature and pH values. Different molar ratios of melamine and formaldehyde were used to synthesize the corresponding resins.
Sami Ullah, M. A. Bustam, M. Nadeem, M. Y. Naz, W. L. Tan, A. M. Shariff   +5 more
doaj   +1 more source