Results 31 to 40 of about 1,961,078 (257)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Implications of the downstream handling of captured CO2

Frontiers in Climate, 2023
Carbon dioxide capture, utilization, and sequestration (CCUS) is a collection of approaches needed to supplement other efforts to achieve net zero carbon emissions.
Fred Mason, Gerald Stokes, Susan Fancy, Volker Sick   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Rapid solubility and mineral storage of CO2 in basalt [PDF]

, 2014
The long-term security of geologic carbon storage is critical to its success and public acceptance. Much of the security risk associated with geological carbon storage stems from its buoyancy.
Gislason S.R et al
core   +1 more source

Theoretical prediction of thermo-physical properties of beef tallow based biodiesel [PDF]

FME Transactions, 2020
This present study deals with the theoretical prediction of thermo-physical properties of waste beef tallow biodiesel by means of developing mathematical correlations using fatty acid esters.
Srinivasan Gokul Raghavendra, Jambulingam Ranjitha   +1 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A rapid transition from ice covered CO2–rich waters to a biologically mediated CO2 sink in the eastern Weddell Gyre [PDF]

, 2007
Circumpolar Deep Water (CDW), locally called Warm Deep Water (WDW), enters the Weddell Gyre in the southeast, roughly at 25° E to 30° E. In December 2002 and January 2003 we studied the effect of entrainment of WDW on the fugacity of carbon dioxide (fCO2)
Hoppema, Mario, Baar, H. J. W., Bakker, D. C. E., Schröder, M., Baar, H. J. W. de, Schroeder, M., Hoppema, M., Schröder, Michael, Geibert, W., de Baar, H. J. W.   +9 more
core   +2 more sources

A multichannel frequency response analyser for impedance spectroscopy on power sources

Journal of Electrochemical Science and Engineering, 2013
A low-cost multi-channel frequency response analyser (FRA) has been developed based on a DAQ (data acquisition)/LabVIEW interface. The system has been tested for electric and electrochemical impedance measurements.
Quentin Meyer, Simon Barass, Oliver Curnick, Tobias Reisch, Daniel J. L. Brett   +4 more
doaj   +1 more source